Adverse Life Events and Pediatric Bipolar Disorder in a Community Mental Health Setting

Marchand, William R.; Wirth, Brigitte; Simon, Mary

doi:10.1007/s10597-005-2600-x

Cited by 46 publications

(33 citation statements)

References 24 publications

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“…Childhood physical or sexual abuse was found to be positively associated with suicidality (14,25), polypharmacy (14), worst response to treatment (32), hallucinations (21), depression severity (22), conduct disorder (25), substance abuse (25), and trauma-related disorders (17,29).…”

Section: Variables Analysismentioning

confidence: 99%

Childhood maltreatment and clinical outcomes of bipolar disorder

Daruy-Filho

Brietzke

Lafer

et al. 2011

Acta Psychiatr Scand

203

150

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Daruy‐Filho L, Brietzke E, Lafer B, Grassi‐Oliveira R. Childhood maltreatment and clinical outcomes of bipolar disorder.Objective: Adverse life events, especially early trauma, play a major role in the course and expression of bipolar disorder (BD). The aim of this article is to present a systematic review about the impact of childhood trauma on the clinical course of BD.Method: A computer‐aided search was performed in Medline, ISI database, EMBASE, PsychInfo, Centre for Reviews and Dissemination, and Databases of Thomson Reuters at April 2011, supplemented by works identified from the reference lists of the first selected papers. Two investigators systematically and independently examined all articles, selecting those according inclusion and exclusion criteria.Results: Four hundred fifteen articles were identified, of which 19 remained in the review after exclusion criteria were applied. In general, childhood maltreatment predicted worsening clinical course of BD. After assessing the quality of the data and of the measurements, childhood maltreatment can be strongly associated to early onset of disorder, suicidality, and substance abuse disorder in patients with BD.Conclusion: Data suggest that childhood abuse and neglect are risk factors associated with worsening clinical course of BD. The conclusions should be interpreted with caution because all the studies included are cross‐sectional and the majority are showing inconsistencies regarding childhood trauma as independent variable and how it is assessed.

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Section: Variables Analysismentioning

confidence: 99%

Childhood maltreatment and clinical outcomes of bipolar disorder

Daruy-Filho

Brietzke

Lafer

et al. 2011

Acta Psychiatr Scand

203

150

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“…Marchand et al [35] reviewed the medical charts of 66 child and adolescent outpatients diagnosed with bipolar disorder (DSM-IV-TR criteria) at a community mental health center. The bipolar group was 67% male and ranged in age from 4 to 17 years (mean 11.3 ± 3.4 years).…”

Section: Childhood Adverse Life Events and Comorbid Anxiety Disordersmentioning

confidence: 99%

Anxiety symptoms and syndromes in bipolar children and adolescents

Jolin

Weller²,

Weller³

2008

Curr Psychiatry Rep

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Anxiety disorders are relatively common in children and adolescents with bipolar disorder. Research to date indicates they may impact the onset, course, and treatment response of bipolar illness in children. Anxiety disorders often precede the onset of pediatric bipolar disorder. Family studies suggest first-degree relatives of bipolar patients are at increased risk for developing mood and anxiety disorders compared with relatives of individuals without mood disorders. Childhood adversity has been associated with higher rates of comorbid anxiety disorders and more severe illness course in bipolar patients. Preliminary study of the neurobiology of bipolar disorder with comorbid anxiety disorders suggests it may be neurophysiologically distinct from bipolar disorder without comorbid anxiety. Bipolar disorder with comorbid anxiety disorders has been associated with greater functional impairment and slower recovery. Prospective, longitudinal studies are needed to help us better understand the relationship between bipolar disorder and comorbid anxiety disorders so that opportunities for early intervention and effective treatment can be realized.

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“…One article (Marchand et al, 2005) did not refer to attachment theory, but to "Reactive Attachment Disorder" in the DSM-IV sense. However the article focused on trauma and complex PTSD as differential diagnoses to PBD, noting: "children with symptoms suggestive of bipolar disorder must be carefully screened for exposure to adverse events.…”

Section: "Reactive Attachment Disorder" (1 Article)mentioning

confidence: 99%