“…This disease has been controlled utilizing two types of vaccines: the wP and aP ones [ 2 ] . The aP vaccines are subunit vaccines that contain pure and inactive components of B. pertussis cells [ 3 , 4 ] , including detoxified pertussis toxin, filamentous hemagglutinin, pertactin, fimbrial antigens and so on. However, the protectivity of the aP vaccines has not been adequate so that several outbreaks has been reported from different countries since 2012 [ 5 , 6 ] .…”