Adverse effects of sports supplements in men

Martin, Sarah; Sherley, Miranda; McLeod, Malcolm D.

doi:10.18773/austprescr.2018.003

Cited by 11 publications

(6 citation statements)

References 16 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another example concerns undeclared anabolic steriods in sports supplements such as the banned substance 1,3-DMAA being marketed as an extract of Aconitum kusnezo i (Cohen, et al, 2018). While their consumption may have the intended effect of increasing the muscle mass for an unaware user, serious adverse effects are common (Martin, et al, 2018). Research in this eld also validates the use of online forums as a source of new leads to illegal practices (Helle, et al, 2019).…”

Section: Introductionmentioning

confidence: 82%

Finding unknown stimulants applied in food supplements using Artificial Intelligence

Gavai¹,

Bouzembrak²,

Bulk³

et al. 2021

Preprint

View full text Add to dashboard Cite

The world market for food supplements is large and is driven by the claims of these products to, for example, treat obesity, increase focus and alertness, decrease appetite, decrease the need for sleep or reduce impulsivity. The use of illegal compounds in food supplements is a continuous threat, certainly because these compounds and products have not been tested for safety by competent authorities. It is therefore of the utmost importance for the competent authorities to know when new products are being marketed and to warn users against potential health risks. In this study we present an approach to detect new and unknown stimulants in food supplements using machine learning. More than 20 new stimulants were identified from two different data sources, namely scientific literature applying word embedding on > 2 million abstracts and articles from formal and social media on the world wide web using text mining. The results show that the developed approach may be suitable to detect “unknowns” in the emerging risk identification activities performed by the competent authorities, which is currently a major hurdle.

show abstract

Section: Introductionmentioning

confidence: 82%

Finding unknown stimulants applied in food supplements using Artificial Intelligence

Gavai¹,

Bouzembrak²,

Bulk³

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…However, caffeine is linked to increases in a person’s heart rate and blood pressure, and may result in an increased sense of anxiety and sleep abnormalities which may negatively impact athletes’ sporting performance. [ 27 , 28 ] The use of banned substances such as anabolic steroids amongst high school athletes was identified in the study by Nolte et al [ 21 ] where 24% of the participants used this banned substance and 4% in the study by Gradidge et al [ 20 ] Anabolic steroids have similar physiological effects on the body as protein supplements; however, anabolic steroids are a form of synthetic testosterone that increase protein synthesis, and as a consequence, increases lean body mass and muscle strength. Anabolic steroids have many side effects that athletes are not always aware of, such as increases in low-density lipoproteins and mood disturbances, typically aggression.…”

Section: Discussionmentioning

confidence: 99%

Sport supplement use among high school rugby players in South Africa: A scoping review

Harmse

Noorbhai

2022

SA J Sports Med

View full text Add to dashboard Cite

Background: The use of sport supplements has increased for all types and levels of sport, with an estimated increase of 5.8% annually. Sport supplement usage and doping among high school athletes has increased over the years to meet the demands of the sports. Objective: This scoping review identifies the trends and gaps in current literature regarding sport supplement use among high school rugby players in South Africa. Methods: A search was conducted using six electronic databases, namely Oxford Academic, Emerald Publishing, ResearchGate, SABINET, PubMed and Google Scholar. The eligibility of the articles was determined by means of a PRISMA flow diagram with the following inclusion criteria: (1) research concerning supplement use among rugby players, (2) research concerning supplement use among high school rugby players. Five articles all comprising of cross-sectional study designs were included in this scoping review. Results: The prevalence of sport supplement use among adolescent rugby players ranged from 30% to 45%. Protein supplements (31% – 79%) were the most commonly identified supplement used among adolescent rugby players with the aim to improve sport performance as the most common reason for use. The internet (74%) and magazines (72%), followed by coaches comments (28% to 30%), were given as the most common sources of information. Conclusion: The use of sport supplements is increasing among high school athletes due to the belief that these substances will provide sporting performance benefits or enhance the competitive ‘edge’ of these athletes. Additional education regarding the safety of supplements is necessary to lower the incidences of doping among young athletes and avoid the adverse health effects that uncontrolled supplement use can cause.

show abstract

“…On the other hand, the improper use of AAS among youth and adolescents causes serious medical problems such as hair loss, acne, sexual and reproductive dysfunction, psychiatric disorder, and an increase in cardiovascular risk (18).…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Analysis and Efficient Separation of Anabolic Androgenic Steroids in Dietary Supplement by a Validated HPTLC Method

et al. 2022

View full text Add to dashboard Cite

Background: Using sports supplements is common among athletes. The presence of anabolic steroids in sports supplements as a hormonal contaminant can increase production efficiency. Since anabolic steroids cause health problems and result in positive doping tests in athletes, it is important to investigate their presence in the supplement preparations consumed by athletes. Objectives: This paper aims to simultaneously determine ten anabolic steroids by high-performance thin-layer chromatography (HPTLC) method in sports supplements. Methods: Chromatographic analysis was conducted on glass silica gel 60F254 plates. The extracts loaded on silica gel plates are subjected to multiple programmed development to separate anabolic androgenic steroids (AASs). Densitometric scanning is carried out at the wavelength of 245 and 366nm. The method was validated according to the ICH guidelines. Results: Spots at retardation factor (Rf) 0.72 (elution system 1), 0.4 (elution system 1), 0.29 (elution system 2), 0.25 (elution system 2), 0.1 (elution system 1), 0.65 (elution system 2), 0.59 (elution system 1), 0.44 (elution system 1), 0.8 (elution system 3), and 0.82 (elution system 3) values were recognized as 19-nor androstenedione, 19-nortestosterone, methyl testosterone, clostebol, stanozolol, trenbolone enanthate, oxymetholone, oxandrolone, testosterone enanthate, and nandrolone decanoate, respectively. The linear ranges were 25 - 250 μg/mL for oxymetholone, 7 - 50 μg/mL for 19-nor androstenedione, 19-nortestosterone, and oxandrolone, and 3 - 20 μg/mL for methyl testosterone, clostebol, stanozolol, trenbolone enanthate, testosterone enanthate, and nandrolone decanoate. The developed method is validated by acceptable precision (CV < 20%) and good accuracy (94% < R < 114%). The value of limit of detection (LOD) for all derivatives was in the range of 0.02 - 0.16 μg/spot (20-160 μg/g of supplement), while limit of quantitation (LOQ) was found to be in the range of 0.06 - 0.5 μg/spot (60 - 500 μg/g of supplement). Fifty sports supplement samples as real ones were collected and analyzed. None of the samples screened positive using the HPTLC method. Conclusions: In the present study, the fast, cheap, and simple HPTLC method could be used for the multi-residue analysis of ten anabolic androgenic steroids in sports supplements.

show abstract

Adverse effects of sports supplements in men

Cited by 11 publications

References 16 publications

Finding unknown stimulants applied in food supplements using Artificial Intelligence

Finding unknown stimulants applied in food supplements using Artificial Intelligence

Sport supplement use among high school rugby players in South Africa: A scoping review

Simultaneous Analysis and Efficient Separation of Anabolic Androgenic Steroids in Dietary Supplement by a Validated HPTLC Method

Contact Info

Product

Resources

About