Adverse effects of maternal rheumatoid arthritis during pregnancy on children

Li, Rong; Ma, Ding; Su, Yazhen; Zhang, Gailian; Xu, Ke; Zhang, Liyun

doi:10.1097/cm9.0000000000001374

Cited by 4 publications

(1 citation statement)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies on autoimmune rheumatological diseases suggest that cytokine‐mediated inflammation is related to the pathogenesis of these disorders 9,10 . Cytokines in maternal circulation play a significant role in inflammation and host defense; changes in these levels can potentially harm the placenta and, thus, affect sensitive fetal organs such as the lungs, brain, and intestines 11 . Therefore, elevated cytokine levels associated with clinical manifestations of RA and AS may be related to adverse pregnancy outcomes.…”

Section: Introductionmentioning

confidence: 99%

Assessment of fetal pulmonary artery Doppler indices in pregnant women with rheumatoid arthritis and ankylosing spondylitis

Beşer

Oluklu

Hendem

et al. 2023

J of Clinical Ultrasound

View full text Add to dashboard Cite

Purpose To investigate fetal pulmonary artery Doppler parameters in pregnant women with rheumatoid arthritis (RA) and ankylosing spondylitis (AS). Methods This case–control study included 24 pregnant women diagnosed with 13 AS and 11 RA and 48 healthy pregnant women at 29–30 weeks of gestation. The demographic and clinical features were recorded, including disease type and duration, attacks during pregnancy, and medications. Pulmonary artery acceleration time (AT), ejection time (ET), and pulmonary artery acceleration time to ejection time (PATET) ratio were measured by manual trace with spectral Doppler ultrasound. Results A shorter pulmonary AT and lower PATET ratio were found in the case group (34.8 ± 2.3, p < 0.001, 0.18 ± 0.02, p < 0.001, respectively). When comparing the groups that had an attack during pregnancy and had not, there were no significant differences in the pulmonary artery indices. We also demonstrated a moderate correlation between maternal disease years and the PATET ratio (r = −0.562, p = 0.004). Conclusion This is the first study to evaluate the effect of RA and AS on fetal pulmonary indices. Maternal inflammation might affect pulmonary development and circulation. Fetal pulmonary Doppler indices can be used to obtain further information about neonatal respiratory morbidities in rheumatological disorders.

show abstract

Section: Introductionmentioning

confidence: 99%

Assessment of fetal pulmonary artery Doppler indices in pregnant women with rheumatoid arthritis and ankylosing spondylitis

Beşer

Oluklu

Hendem

et al. 2023

J of Clinical Ultrasound

View full text Add to dashboard Cite

show abstract

Gene-Environment Interactions During the First Thousand Days Influence Childhood Neurological Diagnosis

Scher¹

2022

Seminars in Pediatric Neurology

View full text Add to dashboard Cite

Pustular psoriasis of pregnancy: A rare cause of placental insufficiency

et al. 2023

View full text Add to dashboard Cite

Generalised pustular psoriasis of pregnancy (GPPP) is a rare dermatosis that presents in the third trimester. It merits careful clinical assessment given the difficulty in diagnosis, impact on maternal health and association with placental insufficiency. We present a case of generalised pustulosis in a pregnant woman at 30 weeks gestation and describe the clinico-pathological challenges in obtaining a diagnosis of GPPP. Furthermore, we provide evidence from cardiotocography and ultrasound of evolving fetal compromise and describe how intensive management can facilitate a positive maternal–fetal outcome.

show abstract

Adverse effects of maternal rheumatoid arthritis during pregnancy on children

Cited by 4 publications

References 10 publications

Assessment of fetal pulmonary artery Doppler indices in pregnant women with rheumatoid arthritis and ankylosing spondylitis

Assessment of fetal pulmonary artery Doppler indices in pregnant women with rheumatoid arthritis and ankylosing spondylitis

Gene-Environment Interactions During the First Thousand Days Influence Childhood Neurological Diagnosis

Pustular psoriasis of pregnancy: A rare cause of placental insufficiency

Contact Info

Product

Resources

About