Adverse Effects of Dipyrone (Metamizole) Use During Pregnancy on Offspring Health: A Systematic Review and Meta-Analysis
Gabriel Moreira Lino,
Felipe Shoji Ishibashi,
George Alessandro Maranhão Conrado
et al.
Abstract:Background This meta-analysis and systematic review aimed to review the health outcomes of offspring following dipyrone use during pregnancy.Methods A systematic literature search was conducted in MEDLINE, Embase, and the Cochrane Library to identify clinical trials or observational studies investigating women who used dipyrone during pregnancy published up to 22 March 2024. Two independent reviewers were responsible for the data extraction. The data were analyzed using odds ratios (ORs) with 95% confidence in… Show more
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