Adverse effects associated with the 577- and 585-nanometer pulsed dye laser in the treatment of cutaneous vascular lesions: A study of 500 patients

Levine, Vicki J.; Geronemus, Roy G.

doi:10.1016/0190-9622(95)90346-1

Cited by 151 publications

(94 citation statements)

References 21 publications

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“…They also contrast with the responses seen using PDL in treating PWS in infants. Although atrophic scarring can occur as a sequelae of PDL for PWS, to our knowledge, severe ulceration rarely, if ever, does so [1][2][3][4]26,27].…”

Section: Discussionmentioning

confidence: 99%

“…In superficial hemangiomas, however, a number of published studies report significant lightening and thinning following treatment with the PDL during the proliferative phase [12][13][14][15][16][17][18] (Table 2). Most reports note a low risk of scarring or other adverse outcome, ranging from none to a rate of 4% [1,[13][14][15][16][17][18]. Some authors advocate early treatment of uncomplicated superficial hemangiomas in the preproliferative or early proliferative phases to prevent further proliferation and associated complications [17,18].…”

Section: Discussionmentioning

confidence: 99%

“…They report best results in superficial, plaque type hemangiomas, noting less effective lightening in hemangiomas with deeper components [12,14,[17][18][19]. Most of these reports have also suggested a very low incidence of scarring or other adverse outcomes when using PDL in the treatment of hemangiomas [1,[13][14][15]. Some have advocated its use in early, otherwise uncomplicated hemangiomas in hopes of preventing further proliferation [17,18].…”

Section: Introductionmentioning

confidence: 99%

“…Pulsed dye laser (PDL) has been used for the treatment of cutaneous vascular anomalies since the late 1980s [1]. It has become a widely accepted treatment for port wine stains (PWS), and is considered a safe and effective treatment, even in very young children [1][2][3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

“…It has become a widely accepted treatment for port wine stains (PWS), and is considered a safe and effective treatment, even in very young children [1][2][3][4][5][6]. Many reports have also noted success using PDL in the treatment of hemangiomas [1,[7][8][9][10][11][12][13][14][15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%

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Complications following pulsed dye laser treatment of superficial hemangiomas

et al. 2006

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Background and ObjectivePulsed dye laser (PDL) has been reported to be safe and effective in the management of superficial hemangiomas of infancy. We report 12 patients with hemangiomas with complications following PDL.Study Design/Materials and MethodsRecords of patients with hemangiomas and a known adverse outcome following PDL were reviewed.ResultsAll were treated early (age range: 5 days to 4 months), and all hemangiomas were facial with a superficial component. Eleven were treated with a 585 nm wavelength, fluence range of 4.7–7 J/cm2, without dynamic cooling. One patient received 7–12 J/cm2 utilizing a 595 nm wavelength with dynamic cooling. In eight cases, treatment led to severe ulceration with subsequent pain, scarring, and in one instance, life‐threatening hemorrhage. In four, permanent atrophic scarring was noted without ulceration.ConclusionsPDL treatment of superficial hemangiomas may rarely lead to significant complications including atrophic scarring and severe ulceration. Lasers Surg. Med. 38:116–123, 2006. © 2006 Wiley‐Liss, Inc.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Complications following pulsed dye laser treatment of superficial hemangiomas

et al. 2006

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Changes in Skin Redness, Pigmentation, Echostructure, Thickness, and Surface Contour After 1 Pulsed Dye Laser Treatment of Port-wine Stains in Children

Hædersdal¹,

Efsen²,

Gniadecka³

et al. 1998

Arch Dermatol

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Background:The pulsed dye laser is the treatment of choice for children with port-wine stains (PWSs). Evaluation of treatment outcome and adverse effects is traditionally based on subjective clinical scoring systems. We intend to objectify treatment results and adverse reactions after 1 treatment with the pulsed dye laser.Design: A before-and-after trial using skin reflectance to detect changes in skin redness and pigmentation, ultrasonography to evaluate changes in echostructure and skin thickness, and 3-dimensional surface contour analysis to detect changes in surface texture.Patients: Twelve children with PWSs.Setting: A university dermatological department. Results:The skin reflectance-determined change in skin redness correlated with the clinical response (r=0.46, PϽ.002). The percentage of reflectance-determined lightening was equal for pink, red, and dark red PWSs (median, 42.9%). Skin pigmentation increased after laser treat-ment (PϽ.007). Ultrasonography revealed lower dermal echogenicity of preoperative PWSs than of postoperative PWSs (PϽ.007) and healthy skin (PϽ.001). An increase in echogenicity reflected a decrease in the dermal water (blood) content. Variations were found in the dermal localization of the PWS. Skin thickness was significantly higher in the PWS before treatment than after (PϽ.001). The preoperative lesional thickness correlated inversely with the ultrasound-assessed treatment response (r=0.35, PϽ.04). The surface contour parameters decreased significantly after laser treatment, indicating a flattening of the skin surface. The contour changes correlated positively with treatment response. By clinical evaluation, no hypopigmentation or texture changes were detected. Conclusion:The evaluation of treatment outcome and adverse effects is refined by the use of skin reflectance, ultrasonographic, and surface contour analysis.

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Eczema as a Complication of Pulsed Dye Laser Therapy

Shahidullah¹,

Frieden²

1999

Archives of Dermatology

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Adverse effects associated with the 577- and 585-nanometer pulsed dye laser in the treatment of cutaneous vascular lesions: A study of 500 patients

Cited by 151 publications

References 21 publications

Complications following pulsed dye laser treatment of superficial hemangiomas

Complications following pulsed dye laser treatment of superficial hemangiomas

Changes in Skin Redness, Pigmentation, Echostructure, Thickness, and Surface Contour After 1 Pulsed Dye Laser Treatment of Port-wine Stains in Children

Eczema as a Complication of Pulsed Dye Laser Therapy

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