Adverse drug events in emergency department patients

Hafner, James Lee; Belknap, Steven M.; Squillante, Marc D.; Bucheit, Kay A.

doi:10.1067/mem.2002.121401

Cited by 155 publications

(142 citation statements)

References 40 publications

Supporting

Mentioning

118

Contrasting

Unclassified

Order By: Relevance

“…La edad de los pacientes con RAM tipo A fue significativamente mayor que la de aquellos con RAM tipo B (p<0,000) (3,26). Fue evidente que a mayor edad, tomaban más medicamentos y se elevaba su riesgo de sufrir RAM, relacionado con la polifarmacia del adulto mayor (20).…”

Section: Discussionunclassified

See 1 more Smart Citation

Reacciones adversas medicamentosas en pacientes que consultaron a instituciones prestadoras de servicios en Pereira, Colombia

Machado‐Alba¹,

Moncada-Escobar²

2006

Rev. salud pública

View full text Add to dashboard Cite

Section: Discussionunclassified

“…Factores que con frecuencia se asocian a RAM son género femenino, edad, tratamiento con citostáticos o antiinfecciosos, antecedentes de RAM y polimedicación (2,3,17,20).…”

unclassified

Reacciones adversas medicamentosas en pacientes que consultaron a instituciones prestadoras de servicios en Pereira, Colombia

Machado‐Alba¹,

Moncada-Escobar²

2006

Rev. salud pública

View full text Add to dashboard Cite

“…Drugs containing digoxin is a cardiac glycosides that commonly used for cardiac insufficiency and speed control in atrial fibrillation. It provides increase of calcium for cell by blocking the sodium-potassium ATPaz pump and so it leads to rising in spasm [21,22]. Also today, drugs containing these active ingredients are frequently used for treatment.…”

Section: Resultsmentioning

confidence: 99%

Investigation Effects of Some Heart Disorder Drugs on Human Carbonic Anhydrase I

Kaplan¹,

Kuzucu²,

Aktaş³

et al. 2017

HJBC

View full text Add to dashboard Cite

K alp rahatsızlıklarının tedavisinde, kan yolu ile etki gösteren metoprolol tartarat ve digoksin ilaçları yaygın bir şekilde kullanılmaktadır. Bu ilaç etken maddelerinin kullanımının hayati öneme sahip olması, bunların kanda bulunan enzimlerin aktiviteleri üzerine inhibisyon etkilerinin araştırılması bu çalışmanın önemi ortaya koymaktadır. Bu çalışmada hedeflenen, metoprolol tartarat ve digoksin ilaç etken maddelerinin insan eritrositi karbonik anhidraz I (CA-I) izoenzimi üzerine in vitro etkilerinin araştırılmasıdır. CA-I izoenzimi Sefaroz-4B-L-tirozin-sülfamid afinite kromatografisi yöntemi ile insan eritrositlerinden saflaştırıldı. CA-I izoenzimi %62 verimle yaklaşık 115 kat saflaştırılmıştır. İnhibisyon çalışmaları sonucunda iki inhibitör de yarışmasız inhibisyon göstermiştir. K i değerleri metoprolol tartarat 5.49±1.86 mM ve digoksin için 0.0914±0.0062 mM olarak belirlenmiştir. Anahtar KelimelerKarbonik anhidraz I, afinite kromotografisi, ilaç, inhibisyon.

show abstract

“…These results were similar to those reported in other studies, which demonstrated the relationship between the process of using drugs and the morbidity and mortality associated with drugs that may trigger adverse reactions. In those studies, problems such as adverse reactions, noncompliance, overdose and inadequate therapy lead to treatment failure, and, if not detected and resolved, may lead to death (Hafner et al, 2002;Lara, Abreu, 2000;Hepler, Strand, 1999;Spina et al, 2008).…”

Section: Difficulty In Taking Medicationmentioning

confidence: 99%

Evaluation of adherence to treatment by patients seen in a psychosocial care center in northeastern Brazil

Souza

Silva

Onofre

et al. 2011

Braz. J. Pharm. Sci.

View full text Add to dashboard Cite

In the treatment of mental disorders, nonadherence to medication, the main cause of psychiatric morbidity, is observed in about 50% of the cases and is responsible for numerous losses. This study evaluated adherence to drug treatment by patients seen in a Psychosocial Care Center (CAPS) in northeastern Brazil. Adherence to treatment was evaluated using the Haynes-Sackett and Morisky-Green-Levine tests. All patients registered in the CAPS were included in the study (n= 101). Only 11.88% of the patients adhered to drug treatment. The main reasons not to use medication were: oblivion (68.83%), feeling unwell after taking the medication (54.22%), not having money to buy the medication (43.83%), not finding the medication in the public health service (39.94%) and fear of harm that might be caused by the drug (28.90%). Furthermore, 85.1% of the patients did not know their diseases, 88.1% did not know their treatment, 86.4% did not feel good when they took their medication, and 88.1% took their medication incorrectly. The results revealed that the lack of information about diseases and drugs used, the nuisance posed by drug therapy and the low access to medications reduce adherence to treatment and, consequently, treatment effectiveness.Uniterms: Treatment adherence. Drug therapy/adherence to treatment. Mental health. Psychosocial Care Center.No tratamento de desordens mentais, a não-adesão ao tratamento ocorre em cerca de 50% dos casos e é responsável por inúmeros prejuízos, além de ser a principal causa de morbidade psiquiátrica. O presente estudo objetivou avaliar a adesão ao tratamento medicamentoso de pacientes atendidos em um Centro de Atenção Psicossocial (CAPS) no Nordeste do Brasil. A avaliação da adesão ao tratamento foi feita através dos testes de Haynes-Sackett e Morisky-Green-Levine. Todos os pacientes cadastrados no CAPS foram incluídos no estudo (n = 101). Observou-se que apenas 11,88% dos pacientes aderiram ao tratamento medicamentoso. As principais razões para o não uso dos medicamentos foram: esquecimento (68,83%), sentir-se mal após a ingestão de medicamentos (54,22%), não ter dinheiro para comprar medicamentos (43,83%), não encontrar os medicamentos no serviço público de saúde (39,94%) e medo dos danos causados pelos medicamentos (28,90%). Além disso, observou-se que 85,1% dos pacientes não conheciam suas doenças, 88,1% não conheciam seus tratamentos, 86,4% não se sentiam bem quando usavam medicamentos e 88,1% usavam os medicamentos incorretamente. Os resultados demonstram que a falta de informação sobre doenças e medicamentos, os danos decorrentes da terapia medicamentosa e o baixo acesso aos medicamentos comprometem a adesão ao tratamento e, consequentemente, a eficácia do tratamento. INTRODUCTIONPoor adherence to medications prescribed for chronic conditions has been cited as a global problem that may lead to increased morbidity and mortality (WHO, 2003; NEHI, 2009). It increases the costs within healthcare systems and contributes to substantial worsening of disease control and quality of life ...

show abstract

Adverse drug events in emergency department patients

Cited by 155 publications

References 40 publications

Reacciones adversas medicamentosas en pacientes que consultaron a instituciones prestadoras de servicios en Pereira, Colombia

Reacciones adversas medicamentosas en pacientes que consultaron a instituciones prestadoras de servicios en Pereira, Colombia

Investigation Effects of Some Heart Disorder Drugs on Human Carbonic Anhydrase I

Evaluation of adherence to treatment by patients seen in a psychosocial care center in northeastern Brazil

Contact Info

Product

Resources

About