Adverse Childhood Experiences from Ages 0–2 and Young Adult Health: Implications for Preventive Screening and Early Intervention

Melville, Alysse

doi:10.1007/s40653-017-0161-0

Cited by 18 publications

(7 citation statements)

References 35 publications

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“…While the dose-response relationship suggests a cumulative effect of ACEs on negative health outcomes (5,44), the influence of age of exposure remains understudied. Most rapid neuroendocrine development occurs from birth to 6 years, therefore implicating early childhood as a sensitive period during which the detrimental impacts of ACEs may be heightened (49). Brain development, endocrine and immune system physiology can be dysregulated by prolonged and unrelenting exposure to stress(ors) (50).…”

Section: Aces: the "Dose-response" Relationshipmentioning

confidence: 99%

The Influence of Adverse Childhood Experiences in Pain Management: Mechanisms, Processes, and Trauma-Informed Care

et al. 2022

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Adverse childhood experiences (ACEs) increase the likelihood of reduced physical and psychological health in adulthood. Though understanding and psychological management of traumatic experiences is growing, the empirical exploration of ACEs and physical clinical outcomes remains under-represented and under-explored. This topical review aimed to highlight the role of ACEs in the experience of chronic pain, pain management services and clinical decision making by: (1) providing an overview of the relationship between ACEs and chronic pain; (2) identifying biopsychosocial mechanisms through which ACEs may increase risk of persistent pain; (3) highlighting the impact of ACEs on patient adherence and completion of pain management treatment; and (4) providing practical clinical implications for pain management. Review findings demonstrated that in chronic pain, ACEs are associated with increased pain complications, pain catastrophizing and depression and the combination of these factors further heightens the risk of early treatment attrition. The pervasive detrimental impacts of the COVID-19 pandemic on ACEs and their cyclical effects on pain are discussed in the context of psychological decline during long treatment waitlists. The review highlights how people with pain can be further supported in pain services by maintaining trauma-informed practices and acknowledging the impact of ACEs on chronic pain and detrimental health outcomes. Clinicians who are ACE-informed have the potential to minimize the negative influence of ACEs on treatment outcomes, ultimately optimizing the impact of pain management services.

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Section: Aces: the "Dose-response" Relationshipmentioning

confidence: 99%

The Influence of Adverse Childhood Experiences in Pain Management: Mechanisms, Processes, and Trauma-Informed Care

et al. 2022

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“…Interaction effects were tested using the nested χ 2 difference test comparing each parameter set to equality versus freely estimated across groups. Lastly, to examine the support for an ACEs cut-off score, we created four different categorical groupings based on prior research with ACEs scores: a) 0 versus 1 or more, b) 0-1 versus 2 or more, c) 0-2 versus 3 or more, and d) 0-3 versus 4 or more (Green et al, 2010;Marie-Mitchell & O'Connor, 2013;McLaughlin et al, 2010;Melville, 2017;Schalinski et al, 2016;Schilling et al, 2007). Again, we used MANCOVA to examine the group differences on the four mental health outcomes, including the same set of covariates.…”

Section: Data Analysesmentioning

confidence: 99%

“…Unfortunately, the extant evidence does not support a universal cut-off score, as the cut-off may be different based on the outcome. In some studies, a cut-off of two or more ACEs showed significant effects on depression and externalizing problems (Karatekin, 2018;Schilling et al, 2007), whereas in others, a cut-off of two or more showed the strongest effects on health-related worry (Melville, 2017) and mood disorders (Green et al, 2010;McLaughlin et al, 2010). Further, some studies showed a score of three or more was significant for behavior problems (Marie-Mitchell & O'Connor, 2013), while other findings demonstrated that a score of four or more ACEs was the best predictor of post-traumatic stress disorder (Schalinski et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

ACEs are not equal: Examining the relative impact of household dysfunction versus childhood maltreatment on mental health in adolescence

Negriff

2020

Social Science & Medicine

150

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“…Timing refers to the years in which the ACEs occur, in this case, “early” or “late.” Duration refers to the exposure of ACEs over successive years, and accumulation refers to the variety of ACEs that have been acquired over a period of time, such as years 1-5. Considerable research has documented that exposure to ACEs as early as the age of five years or younger is associated with negative cognitive, health, and behavioral outcomes in late childhood and across the life course (Hunt, Slack, and Berger 2017; Jimenez et al 2017; McKelvey et al 2017; Melville 2017). For example, studies found that exposure to ACEs by age 5 was strongly associated with externalizing and internalizing behaviors and likelihood of attention deficit hyperactivity disorder (ADHD) diagnosis in middle childhood (also see Jimenez et al 2017).…”

Section: Introductionmentioning

confidence: 99%

Gender Differences in the Accumulation, Timing, and Duration of Childhood Adverse Experiences and Youth Delinquency in Fragile Families

Pierce

Jones

2021

Journal of Research in Crime and Delinquency

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Objective: The purposes of this study are twofold. First, we explore how the accumulation, timing, and duration of ACEs influences youth delinquency. Second, because few studies to date have examined how the effect of ACEs may vary among different groups, we explore how these patterns may vary by gender. Methods: Analyses were based on data from the Fragile Families and Child Wellbeing Study (FFCW), which employs a national sample of urban-born, at-risk youth. Results: The results showed that as the number of early ACEs experienced incrementally increases, the likelihood of youth reporting delinquent behavior also increases, even after adjusting for recent adversity. Moreover, exposure to early ACEs that are high but late, intermittent, or chronically high significantly increase the risk of youth participating in delinquency. Our results also indicate that ACEs are significantly related to delinquency for girls, but not for boys. Conclusions: Prevention and intervention efforts should screen for ACEs—especially in early childhood. Given that the accumulation, timing, and duration of ACE exposure is linked to youth delinquency, interventions that target ACEs early may have greater success at reducing delinquency. Moreover, prevention programs need to consider gender-specific responses to ACEs and gender-specific intervention strategies.

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Adverse Childhood Experiences from Ages 0–2 and Young Adult Health: Implications for Preventive Screening and Early Intervention

Cited by 18 publications

References 35 publications

The Influence of Adverse Childhood Experiences in Pain Management: Mechanisms, Processes, and Trauma-Informed Care

The Influence of Adverse Childhood Experiences in Pain Management: Mechanisms, Processes, and Trauma-Informed Care

ACEs are not equal: Examining the relative impact of household dysfunction versus childhood maltreatment on mental health in adolescence

Gender Differences in the Accumulation, Timing, and Duration of Childhood Adverse Experiences and Youth Delinquency in Fragile Families

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