Adverse alteration of wound flora with topical negative-pressure therapy: a case report

Effectiveness of intraoperative indocyanine-green fluorescence angiography during inguinal lymph node dissection for skin cancer to prevent postoperative wound dehiscence

“…These strategies included preservation of the fascia lata and saphenous vein, primary flap reconstruction, the application of topical negative pressure and the application of a gelatin matrix thrombin tissue sealant [1] to prevent wound dehiscence [5][6][7][8]. However, the most reliable procedure to prevent wound dehiscence after IlnD was trimming off the ischemic part of the flap before wound closure.…”

“…The incidence of postoperative wound dehiscence following inguinal lymph node dissection (IlnD) is higher than that after lymph node dissections in other anatomical regions [1][2][3][4]. In a prospective study of melanoma patients undergoing IlnD, 53 % had some degree of wound dehiscence (wound dehiscence was defined as poor wound healing with a measured defect of at least 1 cm) [1] The explanations that have been proposed for the increased incidence of wound complications associated with IlnD include the greater surface area associated with the dissection, the relatively poor vascular supply to the skin and subcutaneous tissues in that region and the surgical techniques related to the relatively thin skin flaps routinely employed in IlnD [1] Wound dehiscence often leads to extended hospitalization, a reduced quality of life and a delayed return to normal activities, despite several novel approaches that have been applied to prevent or to manage wound dehiscence [5][6][7][8].To resolve these issues, we introduced Icg fluorescence angiography during IlnD to evaluate the blood flow of the skin flap in September 2011 in the Department of Plastic and reconstructive Surgery, University of Hokkaido at Sapporo, graduate School of Medicine. During IlnD, the area of ischemic skin around the groin wound just after lymph node dissection was detected based on…”

Successful Use of Vacuum-Assisted Closure Therapy for Leg Ulcers Caused by Occluding Vasculopathy and Inflammatory Vascular Diseases – A Case Series

“…Wound infections through anaerobe bacteria [8], loss of blood/volume [9] and toxic shock syndrome [10] may be rare complications. Besides pain during the treatment period and especially during change of dressings, in our cases we observed a slight and easily treatable irritation of the area surrounding the wound caused by the foam dressing and the adhesive polyurethane foil.…”

Current Concepts in Negative Pressure Wound Therapy

“…However, results on this issue have been mixed. [28][29][30][31][32][33][34] An early report found a reduction in bacterial loads with NPWT usage in pig wounds inoculated with Staphylococcus epidermidis and Staphylococcus aureus. 5 Other clinical studies have not documented a decrease in wound bacterial loads, 28,31,32 and some have shown an increase.…”