postoperatively was 83,3 (66,7e83,3) in the open group and 58,3 (35,4e66,7) in the minimally invasive group (P ¼ 0.002). This was not statistically significant. Conclusion: No differences were observed between open total gastrectomy and minimally invasive total gastrectomy regarding HRQoL data, collected using the EQ-5D, EORTC QLQ-C30 and EORTC-QLQ-STO22 questionnaires.