Advancing One human–animal–environment Health for global health security: what does the evidence say?

Zinsstag, Jakob; Kaiser-Grolimund, Andrea; Heitz-Tokpa, Kathrin; Sreedharan, Rajesh; Liu, Juan; Caya, F; Stone, M. B.; Brown, Hannah; Bonfoh, Bassirou; Dobell, Emily; Morgan, Dilys; Homaira, Nusrat; Kock, Richard; Hattendorf, Jan; Crump, Lisa; Mauti, Stephanie; Vilas, Victor del Rio; Saikat, Sohel; Zumla, Alimuddin; Heymann, David L.; Dar, Osman; Rocque, Stéphane De La

doi:10.1016/s0140-6736(22)01595-1

Cited by 67 publications

(48 citation statements)

References 65 publications

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“…Coordination between sectors, primarily human, animal and environment health, is critical for timely and effective preparedness and response measures in countries. 1 As such, countries welcome guidance and benefit from extensive global partnership to operationalise many multisectoral, ‘One Health’ approaches needed for the identification and management of emerging, re-emerging and endemic health threats. 2–4 The Tripartite–the Food and Agriculture Organization of the United Nations (FAO), the World Health Organization (WHO), and the World Organisation for Animal Health (WOAH)–operationalised their collaboration during the H5N1 avian influenza epidemic that began in 2003 and this materialised in experienced coordination and joint investment in the ‘Tripartite’, recognising ‘a shared responsibility in the management of zoonotic diseases and other threats at the human-animal-environment interface’.…”

Section: Introductionmentioning

confidence: 99%

“…The global crisis brought on by the COVID-19 pandemic demonstrates how pathogen transmission between animals, humans and their shared environment can impact all aspects of society. Coordination between sectors, primarily human, animal and environment health, is critical for timely and effective preparedness and response measures in countries 1. As such, countries welcome guidance and benefit from extensive global partnership to operationalise many multisectoral, ‘One Health’ approaches needed for the identification and management of emerging, re-emerging and endemic health threats 2–4.…”

Section: Introductionmentioning

confidence: 99%

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One health systems strengthening in countries: Tripartite tools and approaches at the human-animal-environment interface

et al. 2023

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Unexpected pathogen transmission between animals, humans and their shared environments can impact all aspects of society. The Tripartite organisations—the Food and Agriculture Organization of the United Nations (FAO), the World Health Organization (WHO), and the World Organisation for Animal Health (WOAH)—have been collaborating for over two decades. The inclusion of the United Nations Environment Program (UNEP) with the Tripartite, forming the ‘Quadripartite’ in 2021, creates a new and important avenue to engage environment sectors in the development of additional tools and resources for One Health coordination and improved health security globally. Beginning formally in 2010, the Tripartite set out strategic directions for the coordination of global activities to address health risks at the human-animal-environment interface. This paper highlights the historical background of this collaboration in the specific area of health security, using country examples to demonstrate lessons learnt and the evolution and pairing of Tripartite programmes and processes to jointly develop and deliver capacity strengthening tools to countries and strengthen performance for iterative evaluations. Evaluation frameworks, such as the International Health Regulations (IHR) Monitoring and Evaluation Framework, the WOAH Performance of Veterinary Services (PVS) Pathway and the FAO multisectoral evaluation tools for epidemiology and surveillance, support a shared global vision for health security, ultimately serving to inform decision making and provide a systematic approach for improved One Health capacity strengthening in countries. Supported by the IHR-PVS National Bridging Workshops and the development of the Tripartite Zoonoses Guide and related operational tools, the Tripartite and now Quadripartite, are working alongside countries to address critical gaps at the human-animal-environment interface.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

One health systems strengthening in countries: Tripartite tools and approaches at the human-animal-environment interface

et al. 2023

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“…Global health security (GHS) aims, further, to reduce the threat from and impact of acute public health events across regions and international boundaries (see reference 1 for a critique of GHS). Factors affecting both are the politicisation of public health, colonial structures, changing populations, urbanisation, mobility of people and goods, farming practices, wildlife trade, wars, climate change, and environmental degradation, which can all increase the risk of emerging and re-emerging infectious diseases and ecological disasters,2 and reflect the need for a One Health approach 3–6. One Health and the incorporation of planetary boundaries into planning and management are required for a sustainable future 2 3…”

Section: Introductionmentioning

confidence: 99%

Addressing the challenges of implementing evidence-based prioritisation in global health

et al. 2023

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Global health requires evidence-based approaches to improve health and decrease inequalities. In a roundtable discussion between health practitioners, funders, academics and policy-makers, we recognised key areas for improvement to deliver better-informed, sustainable and equitable global health practices. These focus on considering information-sharing mechanisms and developing evidence-based frameworks that take an adaptive function-based approach, grounded in the ability to perform and respond to prioritised needs. Increasing social engagement as well as sector and participant diversity in whole-of-society decision-making, and collaborating with and optimising on hyperlocal and global regional entities, will improve prioritisation of global health capabilities. Since the skills required to navigate drivers of pandemics, and the challenges in prioritising, capacity building and response do not sit squarely in the health sector, it is essential to integrate expertise from a broad range of fields to maximise on available knowledge during decision-making and system development. Here, we review the current assessment tools and provide seven discussion points for how improvements to implementation of evidence-based prioritisation can improve global health.

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“…One Health − is not completely novel, as already in the 19th century the famed pathologist Rudolf Virchow recognized the importance of health issues at the interface of humans, animals, and the environment . However, surely novel is its use in the context of the R&D pharmaceutical pipeline.…”

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confidence: 99%

Harnessing the 12 Green Chemistry Principles for Sustainable Antiparasitic Drugs: Toward the One Health Approach

Martinengo,

Diamanti,

Uliassi

et al. 2024

ACS Infect. Dis.

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Antiparasitic drug development stands as a critical endeavor in combating infectious diseases which, by affecting the well-being of humans, animals, and the environment, pose significant global health challenges. In a scenario where conventional pharmacological interventions have proven inadequate, the One Health approach, which emphasizes interdisciplinary collaboration and holistic solutions, emerges as a vital strategy. By advocating for the integration of One Health principles into the R&D pharmaceutical pipeline, this Perspective promotes green chemistry methodologies to foster the development of environmentally friendly antiparasitic drugs for both human and animal health. Moreover, it highlights the urgent need to address vector-borne parasitic diseases (VBPDs) within the context of One Health-driven sustainable development, underscoring the pivotal role of medicinal chemists in driving transformative change. Aligned with the Sustainable Development Goals (SDGs) and the European Green Deal, this Perspective explores the application of the 12 Principles of Green Chemistry as a systematic framework to guide drug discovery and production efforts in the context of VBPD. Through interdisciplinary collaboration and a constant commitment to sustainability, the field can overcome the challenges posed by VBPD while promoting global and environmental responsibility. Serving as a call to action, scientists are urged to integrate One Health concepts and green chemistry principles into routine drug development practices, thereby paving the way for a more sustainable R&D pharmaceutical pipeline for antiparasitic drugs.

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Advancing One human–animal–environment Health for global health security: what does the evidence say?

Cited by 67 publications

References 65 publications

One health systems strengthening in countries: Tripartite tools and approaches at the human-animal-environment interface

One health systems strengthening in countries: Tripartite tools and approaches at the human-animal-environment interface

Addressing the challenges of implementing evidence-based prioritisation in global health

Harnessing the 12 Green Chemistry Principles for Sustainable Antiparasitic Drugs: Toward the One Health Approach

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