Advancing Maternal Age and Low-Dose Aspirin Effect in Poor Responders Undergoing In Vitro Fertilization

Low-dose aspirin use does not improve in vitro fertilization outcomes in poor responders

“…This was postulated to come from aspirin's properties of prostaglandin inhibition, in which implantation might be compromised. Other investigators have also shown a similar trend toward improvement in nonaspirin cohorts (20). Likewise, we also noted a slight decrease in the implantation rates for patients using aspirin.…”

“…Recently, studies have suggested that aspirin is not as beneficial as originally thought (13,14,(18)(19)(20)(21)(22). Hurst et al (14) found that after oocyte retrieval patients on aspirin had a decrease in implantation rate.…”

“…Few studies, with limited powers, have evaluated the efficacy of aspirin use in poor-responder patients undergoing IVF (13)(14)(15)(16)(17)(18)(19)(20). Our study focused on whether aspirin therapy improved IVF outcomes in patients with a diagnosis as poor responders.…”