Advancing immunotherapy for melanoma: the critical role of single-cell analysis in identifying predictive biomarkers
Ru He,
Jiaan Lu,
Jianglong Feng
et al.
Abstract:Melanoma, a malignant skin cancer arising from melanocytes, exhibits rapid metastasis and a high mortality rate, especially in advanced stages. Current treatment modalities, including surgery, radiation, and immunotherapy, offer limited success, with immunotherapy using immune checkpoint inhibitors (ICIs) being the most promising. However, the high mortality rate underscores the urgent need for robust, non-invasive biomarkers to predict patient response to adjuvant therapies. The immune microenvironment of mel… Show more
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