Advancing Cancer Treatment Through Nanotechnology Driven Immunotherapy for Pancreatic Cancer
Sreejith T,
Kaladhar Kamalasanan,
Sneha S
et al.
Abstract:Pancreatic
cancer is expected to be the most lethal cancer by 2030;
among that, PDAC is the most prominent one, which is immune resistant,
posing substantial hurdles to creating effective therapeutics. Despite
the advancements in immunotherapy, its application in PDAC is less
successful. Uniquely, PDAC tumors are “cold” to immune
response mainly due to suppression of spatiotemporal immune signatures
from cells and tumor microenvironment. Contrary to other immune-responsive
tumors, immunotherapy in combination … Show more
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