Advances in the synthesis of aromatic and heteroaromatic carboxylic acids and their esters

Visible-light-driven photocatalytic carboxylation to aromatic carboxylic acids with CO2

“…(Hetero)aromatic carboxylic acids and their derivatives, which are considered an important class of compounds, are widely utilized in the food industry, medicine and veterinary fields, and synthesis of biologically active molecules, dyes, polymers, agricultural chemicals, and corrosion inhibitors. [1][2][3][4] Their industrial synthesis mainly involves the oxidation of alkyl-, alkenyl-, and alkynylaromatic compounds. [5][6][7] Because of the extensive application of aryl carboxylic acids and their derivatives, more efficient alternative methods for synthesizing them are constantly developed.…”

Direct Microdroplet Synthesis of Carboxylic Acids from Alcohols by Preparative Paper Spray Ionization without Phase Transfer Catalysts

“…Comprising a significant ingredient of the human diet, acids are found in almost all plant-derived foods, which are endogenously synthesized for protection against UV light, insects, viruses and bacteria . In consideration of the significance and the above applications, the synthesis of aromatic acids has been extensively studied …”

“…2 In consideration of the significance and the above applications, the synthesis of aromatic acids has been extensively studied. 3 Traditionally, acids have been synthesized by the oxidation of hydrocarbons, 4 alcohols and aldehydes, and the oxidative cracking of olefins and alkynes. 5 The oxidation reactions from these reactants are typically carried out in highly oxidative environments (using HNO 3 , KMnO 4 , K 2 Cr 2 O 7 , etc.).…”