2021
DOI: 10.1080/14656566.2021.1873950
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Advances in the pharmacological management of neutropenia in solid tumors: the advent of biosimilars

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“…Several biosimilars of the originator drugs filgrastim and pegfilgrastim are now approved in different regions of the world [70][71][72], several of them according to the strict requirements of the US Food and Drug Administration (FDA) and European Medicines Agency (EMA). There are no differences in clinical efficacy and side effects compared to the original filgrastim or pegfilgrastim preparation [73]. Approved biosimilars of filgrastim can also be used for stem cell mobilization in healthy individuals [20].…”
Section: Biosimilars Of Filgrastim and Pegfilgrastimmentioning
confidence: 99%
“…Several biosimilars of the originator drugs filgrastim and pegfilgrastim are now approved in different regions of the world [70][71][72], several of them according to the strict requirements of the US Food and Drug Administration (FDA) and European Medicines Agency (EMA). There are no differences in clinical efficacy and side effects compared to the original filgrastim or pegfilgrastim preparation [73]. Approved biosimilars of filgrastim can also be used for stem cell mobilization in healthy individuals [20].…”
Section: Biosimilars Of Filgrastim and Pegfilgrastimmentioning
confidence: 99%