Advances in the application of computational fluid dynamics in cardiovascular flow

Kumar, Nitesh; Ganesha, A; Girish, H; Shenoy, B. Gowrava

doi:10.1080/23311916.2023.2178367

Cogent Engineering

2023

DOI: 10.1080/23311916.2023.2178367

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Advances in the application of computational fluid dynamics in cardiovascular flow

Nitesh Kumar

A Ganesha

H Girish

et al.

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2023

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Cited by 3 publications

(7 citation statements)

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“…[1,2] Median survival time of patients diagnosed with PHA is only 5 months. [3] The difficulty in diagnosing hepatic angiosarcoma is due the lack of any specific tumor markers and specific imaging findings. Seventy-five percent of the tumors have no definitive etiology.…”

mentioning

confidence: 99%

“…[4] It is associated with malignant transformation usually seen in relation to exposure to polyvinyl chloride, arsenic, Thorotrast, and radiation. [1,3,4]…”

mentioning

confidence: 99%

“…[6] Surgical resection of the liver remains the mainstay of treatment, because there is no effective chemotherapy regimen suggested in the literature, although they are being given as palliation. [3] In literature, surgical resection with adjutant chemotherapy has increased the median survival to 40.5 months. [1–3]…”

mentioning

confidence: 99%

“…Primary hepatic angiosarcoma (PHA) is a rare malignant tumor arising from the endothelial cells in the liver, which accounts for 1% of all primary hepatic tumors with males being more affected than females (4:1). [1–3] Most common primary hepatic malignancies intrahepatic cholangiocarcinoma followed by hepatocellular carcinoma, with PHA being third in line. [1,2] Median survival time of patients diagnosed with PHA is only 5 months.…”

mentioning

confidence: 99%

“…[3] In literature, surgical resection with adjutant chemotherapy has increased the median survival to 40.5 months. [1–3]…”

mentioning

confidence: 99%

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Cystic presentation of primary hepatic angiosarcoma

et al. 2023

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mentioning

confidence: 99%

“…[4] It is associated with malignant transformation usually seen in relation to exposure to polyvinyl chloride, arsenic, Thorotrast, and radiation. [1,3,4]…”

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

“…[3] In literature, surgical resection with adjutant chemotherapy has increased the median survival to 40.5 months. [1–3]…”

mentioning

confidence: 99%

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Cystic presentation of primary hepatic angiosarcoma

et al. 2023

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A Computational Fluid Dynamics Study to Compare Two Types of Arterial Cannulae for Cardiopulmonary Bypass

Gramigna,

Palumbo,

Rossi

et al. 2023

Fluids

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Thanks to recent technological and IT advances, there have been rapid developments in biomedical and health research applications of computational fluid dynamics. This is a methodology of computer-based simulation that uses numerical solutions of the governing equations to simulate real fluid flows. The aim of this study is to investigate, using a patient-specific computational fluid dynamics analysis, the hemodynamic behavior of two arterial cannulae, with two different geometries, used in clinical practice during cardiopulmonary bypass. A realistic 3D model of the aorta is extracted from a subject’s CT images using segmentation and reverse engineering techniques. The two cannulae, with similar geometry except for the distal end (straight or curved tip), are modeled and inserted at the specific position in the ascending aorta. The assumption of equal boundary conditions is adopted for the two simulations in order to analyze only the effects of a cannula’s geometry on hemodynamic behavior. Simulation results showed a greater percentage of the total output directed towards the supra-aortic vessels with the curved tip cannula (66% vs. 54%), demonstrating that the different cannula tips geometry produces specific advantages during cardiopulmonary bypass. Indeed, the straight one seems to generate a steadier flow pattern with good recirculation in the ascending aorta.

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A Mini Review on Fluid Topology Optimization

Li,

Wang,

Zhang

et al. 2023

Materials

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Topology optimization holds great potential to achieve the best performance for various fluid-related applications like aircraft components and microfluidic mixers. This paper reviews comprehensively the technical progress of this field over the last decade from the viewpoint of structural expression. The density-based approach has been widely adopted to design structures due to its simple concept, ease of implementation, and robustness. Different designs using such a pointwise method for systems under Stokes, laminar Navier–Stokes, turbulent, non-Newtonian, and steady-state/unsteady-state fluid flows are reviewed and discussed in depth. Both isogeometric analysis and the moving morphable components/voids methods will demonstrate their advantages regarding integration with computer-aided design. The moving morphable components/voids method also significantly reduces computing costs. From the viewpoint of boundary smoothness, we are most concerned about whether smoother boundaries can reduce objective functions such as energy dissipation even lower. Therefore, this work also concentrates on level set and spline expression methods. Furthermore, we identify isogeometric analysis and machine learning in shaping the field’s future. In addition, the review highlights the following two challenges: achieving accurate fluid model construction and the relatively limited experimental validation of fluid topology optimization outcomes.

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Advances in the application of computational fluid dynamics in cardiovascular flow

Cited by 3 publications

References 99 publications

Cystic presentation of primary hepatic angiosarcoma

Cystic presentation of primary hepatic angiosarcoma

A Computational Fluid Dynamics Study to Compare Two Types of Arterial Cannulae for Cardiopulmonary Bypass

A Mini Review on Fluid Topology Optimization

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