Advances in testing for human papillomavirus-mediated head and neck cancer
Hisham Mehanna,
Laia Alemany,
Christian von Buchwald
Abstract:Purpose of review
New evidence has recently emerged regarding the utility and benefits of dual p16INKa (p16) and Human papillomavirus (HPV) status testing when determining the diagnosis and prognosis of patients with oropharyngeal cancer.
Recent findings
HPV RNA polymerase chain reaction (PCR) is the most accurate diagnostic test. The other assays (HPV DNA PCR, HPV DNA/RNA in-situ hybridization (ISH) and p16) applied to formalin fixed tumour tissue have… Show more
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