Advances in skin cancer prevention: From UV radiation and risk factors to effective public health interventions

Abstract

Skin cancer remains a significant public health concern, with rising incidence rates worldwide. Our literature review examines current knowledge on skin cancer prevention, focusing on key areas such as epidemiology, risk factors, ultraviolet (UV) radiation exposure, pathophysiological and genetic mechanisms, and prevention strategies. A comprehensive literature search was conducted across databases including PubMed, Scopus, Web of Science, and Google Scholar, focusing on peer-reviewed articles published from 2013 to 2023. Non-peer-reviewed articles, non-English studies, non-human research, and studies published before 2013 were excluded. Our study highlights the significant role of UV radiation in skin cancer pathogenesis and underscores the importance of comprehensive prevention strategies. Sunscreen use and protective behaviors are effective but underutilized. Community-based interventions show promise in increasing public awareness and promoting protective measures. Screening and chemoprevention offer additional avenues for reducing skin cancer burden. The findings emphasize the need for continued public health efforts to enhance skin cancer prevention and early detection. Future research should focus on optimizing prevention strategies and exploring novel approaches to reduce the incidence of skin cancer.