Advances in paper-analytical methods for pharmaceutical analysis

Sharma, Niraj; Barstis, T. L. O.; Giri, Basant

doi:10.1016/j.ejps.2017.09.031

Cited by 37 publications

(23 citation statements)

References 84 publications

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“…The demand for sensors in the pharmaceutical industry comes from several needs such as the quality control of pharmaceuticals, analysis of biological fluids, and investigation of pharmaceutical residues in the environment . The first work regarding the quality control of pharmaceuticals was based on the construction of a microfluidic paper‐based sensor for the separation and detection of paracetamol and 4‐aminophenol using chronoamperometry.…”

Section: Applications Of Paper Devicessupporting

confidence: 81%

Emerging Considerations for the Future Development of Electrochemical Paper‐Based Analytical Devices

et al. 2018

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Meeting the current needs for easier, more precise and faster analyses that also follow the principles of green analytical chemistry requires novel analytical chemistry strategies. Since the appearance in this century of the first device based on a paper platform, many studies have been presented in the literature, providing a wide range of designs and possibilities for the application of paper platforms to electroanalytical systems. This Review gives an overview of the field and can pave the way for the future development of electrochemical paper‐based analytical devices. We also present a critical point of view regarding what has been investigated and developed and what is still missing. This Review discusses the efforts made in the field related to important topics such as the choice of the paper substrate, the device construction process, the characterization of the device, and applications in different areas. In this way, we indicate some steps necessary for optimizing the design of the devices, with a focus on multidisciplinary collaborations that could move entire systems from the bench of the laboratory to the field.

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Section: Applications Of Paper Devicessupporting

confidence: 81%

Emerging Considerations for the Future Development of Electrochemical Paper‐Based Analytical Devices

et al. 2018

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“…The fluid flow in µPADs depends on capillary action and does not require pumping of liquids. µPADs are low‐cost, disposable, simple‐to‐use analytical devices applicable in low‐resource settings . The colorimetric detection is promising, especially in combination with image processing software on smartphones.…”

Section: Analytical Technologies For the Detection Of Pharmaceutical mentioning

confidence: 99%

Materials and Technologies to Combat Counterfeiting of Pharmaceuticals: Current and Future Problem Tackling

et al. 2020

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The globalization of drug trade leads to the expansion of pharmaceutical counterfeiting. The immense threat of low quality drugs to millions of patients is considered to be an under‐addressed global health challenge. Analytical authentication technologies are the most effective methods to identify active pharmaceutical ingredients and impurities. However, most of these analytical testing techniques are expensive and need skilled personnel. To combat counterfeiting of drugs, the package of an increasing number of drugs is being protected through advanced package labeling technologies. Though, package labeling is only effective if the drugs are not repackaged. Therefore “in‐drug labeling,” instead of “drug package labeling,” may become powerful tools to protect drugs. This review aims to overview how advanced micro‐ and nanomaterials might become interesting markers for the labeling of tablets and capsules. Clearly, how well such identifiers can be integrated into “solid drugs” without compromising drug safety and efficacy remains a challenge. Also, incorporation of tags has so far only been reported for the protection of solid drug dosage forms. No doubts that in‐drug labeling technologies for “liquid drugs,” like injectables which contain expensive peptides, monoclonal antibodies, vaccines, dermal fillers, could help to protect them from counterfeiting as well.

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“…Nitric acid and Mandelin's reagents can be used to differentiate codeine from other opiates due to the noticeably different colors they produce for different opiates. Although these colorimetric methods are simple and rapid, most of the chromogenic reagents give similar color responses in the presence of different opioid drugs, making these techniques lack selectivity [16].…”

Section: Colorimetric Assaysmentioning

confidence: 99%

A Review of Analytical Methods for Codeine Determination

et al. 2021

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Codeine is derived from morphine, an opioid analgesic, and has weaker analgesic and sedative effects than the parent molecule. This weak opioid is commonly used in combination with other drugs for over-the-counter cough relief medication. Due to the psychoactive properties of opioid drugs, the easily obtained codeine often becomes subject to misuse. Codeine misuse has emerged as a concerning public health issue due to its associated adverse effects such as headache, nausea, vomiting, and hemorrhage. Thus, it is very important to develop reliable analytical techniques to detect codeine for both quality control of pharmaceutical formulations and identifying drug misuse in the community. This review aims to provide critical outlooks on analytical methods applicable to the determination of codeine.

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Advances in paper-analytical methods for pharmaceutical analysis

Cited by 37 publications

References 84 publications

Emerging Considerations for the Future Development of Electrochemical Paper‐Based Analytical Devices

Emerging Considerations for the Future Development of Electrochemical Paper‐Based Analytical Devices

Materials and Technologies to Combat Counterfeiting of Pharmaceuticals: Current and Future Problem Tackling

A Review of Analytical Methods for Codeine Determination

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