Advances in Nanocarriers for Delivering Therapeutic Agents Against Hepatitis B Virus
Jia Li,
Jianlan Yuan,
Hugang Li
et al.
Abstract:Hepatitis B virus (HBV) infection is a crucial public health issue and a major cause of liver disease, such as cirrhosis and hepatocellular carcinoma. At present, orally administered small molecule drugs, such as nucleoside / nucleotide analogues, are recommended as the first‐line treatment for HBV. However, the therapeutic efficacy of these drugs is hindered by off‐target toxicity caused by the whole‐body permeation distribution of these oral drugs. As an emerging drug delivery technology, systemically admini… Show more
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