Advances in modified antimicrobial peptides as marine antifouling material

Saha, Rituparna; Bhattacharya, Debalina; Mukhopadhyay, Mainak

doi:10.1016/j.colsurfb.2022.112900

Cited by 14 publications

(8 citation statements)

References 74 publications

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“…The molecular process of membrane penetration and the disruption of AMPs depends on various variables, such as the sequence of amino acids in the membrane, the amount of peptides, and the lipids in the membrane [ 39 ]. Almost all AMPs tend to be classified into two mechanistic pathways depending on their cell membrane interaction [ 61 , 62 , 63 , 64 ]. The first category focuses on cell wall disruption peptides that can distinguish between bacterial and human or host cells [ 43 , 65 , 66 , 67 ], and their cell wall penetrative properties include the following models: carpet, staves of a barrel, micellar aggregate, and toroidal pores (e.g., magainin-2, protegrin-1) [ 39 , 67 ].…”

Section: Antimicrobial Peptides (Amps) With Anticancer Potentialmentioning

confidence: 99%

“…Therefore, with the rise of AMPs in the volume outside the bacterial cells, different reactions eventually lead to the induction of apoptosis (inflammation or electrolyte disequilibrium) [ 62 , 68 ]. The second category of AMPs focuses on non-disruptive cell wall interactions (intracellular targets—altering protein synthesis, enzyme activity, binding, and interfering in DNA and RNA replication) [ 39 , 63 , 67 ]. Buforins are included in the latest category.…”

Section: Antimicrobial Peptides (Amps) With Anticancer Potentialmentioning

confidence: 99%

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Anticancer Potential of Antimicrobial Peptides: Focus on Buforins

Tolos (Vasii),

Moisa,

Dochia

et al. 2024

Polymers

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In seeking alternative cancer treatments, antimicrobial peptides (AMPs), sourced from various life forms, emerge as promising contenders. These endogenous peptides, also known as host defense peptides (HDPs), play crucial roles in immune defenses against infections and exhibit potential in combating cancers. With their diverse defensive functions, plant-derived AMPs, such as thionins and defensins, offer a rich repertoire of antimicrobial properties. Insects, amphibians, and animals contribute unique AMPs like cecropins, temporins, and cathelicidins, showcasing broad-spectrum activities against bacteria, fungi, and viruses. Understanding these natural peptides holds significant potential for developing effective and targeted therapies against cancer and infectious diseases. Antimicrobial peptides (AMPs) exhibit diverse structural characteristics, including α-helical, β-sheet, extended, and loop peptides. Environmental conditions influence their structure, connecting to changes in cell membrane hydrophobicity. AMPs’ actions involve direct killing and immune regulation, with additional activities like membrane depolarization. In this review, we focus on antimicrobial peptides that act as anticancer agents and AMPs that exhibit mechanisms akin to antimicrobial activity. Buforin AMPs, particularly Buforin I and II, derived from histone H2A, demonstrate antibacterial and anticancer potential. Buforin IIb and its analogs show promise, with selectivity for cancer cells. Despite the challenges, AMPs offer a unique approach to combat microbial resistance and potential cancer treatment. In various cancer types, including HeLa, breast, lung, ovarian, prostate, and liver cancers, buforins demonstrate inhibitory effects and apoptosis induction. To address limitations like stability and bioavailability, researchers explore buforin-containing bioconjugates, covalently linked with nanoparticles or liposomes. Bioconjugation enhances specificity-controlled release and combats drug resistance, presenting a promising avenue for targeted cancer treatment. Clinical translation awaits further evaluation through in vivo studies and future clinical trials.

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Section: Antimicrobial Peptides (Amps) With Anticancer Potentialmentioning

confidence: 99%

Section: Antimicrobial Peptides (Amps) With Anticancer Potentialmentioning

confidence: 99%

Anticancer Potential of Antimicrobial Peptides: Focus on Buforins

Tolos (Vasii),

Moisa,

Dochia

et al. 2024

Polymers

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“…The non-hydrogen bonding peptoid backbone played a primary role in minimizing their adhesion strength to the modified surfaces. Consequently, the adhesion strength and initial attachment properties of N. incerta were significantly reduced on surfaces containing peptoid-PEO coatings, underscoring the crucial role of peptide-polymer conjugation in marine antifouling applications [74]. Combining the surface microstructure and low-surface-energy substance modifications to achieve synergistic antifouling surfaces holds significant application potential and research prospects.…”

Section: Antifouling Strategies Based On Marine Biological Secretionsmentioning

confidence: 99%

Research Progress on Low-Surface-Energy Antifouling Coatings for Ship Hulls: A Review

Cao,

Cao

2023

Biomimetics

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The adhesion of marine-fouling organisms to ships significantly increases the hull surface resistance and expedites hull material corrosion. This review delves into the marine biofouling mechanism on marine material surfaces, analyzing the fouling organism adhesion process on hull surfaces and common desorption methods. It highlights the crucial role played by surface energy in antifouling and drag reduction on hulls. The paper primarily concentrates on low-surface-energy antifouling coatings, such as organic silicon and organic fluorine, for ship hull antifouling and drag reduction. Furthermore, it explores the antifouling mechanisms of silicon-based and fluorine-based low-surface-energy antifouling coatings, elucidating their respective advantages and limitations in real-world applications. This review also investigates the antifouling effectiveness of bionic microstructures based on the self-cleaning abilities of natural organisms. It provides a thorough analysis of antifouling and drag reduction theories and preparation methods linked to marine organism surface microstructures, while also clarifying the relationship between microstructure surface antifouling and surface hydrophobicity. Furthermore, it reviews the impact of antibacterial agents, especially antibacterial peptides, on fouling organisms’ adhesion to substrate surfaces and compares the differing effects of surface structure and substances on ship surface antifouling. The paper outlines the potential applications and future directions for low-surface-energy antifouling coating technology.

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“…Therefore, the phenomenon brings numerous inconveniences and substantial economic losses . Additionally, the bacterial adhesion and growth on the surfaces of food processing equipment, marine transportation equipment, and medical devices increases the risks of food spoilage, transportation cost, and implant infection. − …”

Section: Introductionmentioning

confidence: 99%

Bioinspired Photoelectronic Synergy Coating with Antifogging and Antibacterial Properties

Gao,

Xing,

Liu

et al. 2024

Langmuir

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Optically transparent glass with antifogging and antibacterial properties is in high demand for endoscopes, goggles, and medical display equipment. However, many of the previously reported coatings have limitations in terms of long-term antifogging and efficient antibacterial properties, environmental friendliness, and versatility. In this study, inspired by catfish and sphagnum moss, a novel photoelectronic synergy antifogging and antibacterial coating was prepared by cross-linking polyethylenimine-modified titanium dioxide (PEI-TiO 2 ), polyvinylpyrrolidone (PVP), and poly(acrylic acid) (PAA). The asprepared coating could remain fog-free under hot steam for more than 40 min. The experimental results indicate that the long-term antifogging properties are due to the water absorption and spreading characteristics. Moreover, the organic−inorganic hybrid of PEI and TiO 2 was first applied to enhance the antibacterial performance. The Staphylococcus aureus and the Escherichia coli growth inhibition rates of the as-prepared coating reached 97 and 96% respectively. A photoelectronic synergy antifogging and antibacterial mechanism based on the positive electrical and photocatalytic properties of PEI-TiO 2 was proposed. This investigation provides insight into designing multifunctional bioinspired surface materials to realize antifogging and antibacterial that can be applied to medicine and daily lives.

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Advances in modified antimicrobial peptides as marine antifouling material

Cited by 14 publications

References 74 publications

Anticancer Potential of Antimicrobial Peptides: Focus on Buforins

Anticancer Potential of Antimicrobial Peptides: Focus on Buforins

Research Progress on Low-Surface-Energy Antifouling Coatings for Ship Hulls: A Review

Bioinspired Photoelectronic Synergy Coating with Antifogging and Antibacterial Properties

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