Advances in MicroRNA-Mediated Regulation of Cardiomyocyte Injury After Coronary Microembolization
Lange Li,
Yaxuan Zheng,
Kun Li
et al.
Abstract:Coronary microembolization (CME) occurs in patients with acute coronary syndrome and is caused primarily by atherosclerotic plaque rupture associated with surgery. CME can lead to arrhythmias, decreased coronary blood flow reserve, and cardiac systolic dysfunction. The clinical efficacy of conventional coronary artery dilation, antiplatelet agents, and direct thrombus aspiration after CME is not satisfactory. Studies have indicated that microRNAs (miRNAs) specifically bind the 3′ untranslated regions (UTRs) of… Show more
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