Advances in macrophage-myofibroblast transformation in fibrotic diseases
Jia-Qi Ban,
Li-Hong Ao,
Xiu He
et al.
Abstract:Macrophage-myofibroblast transformation (MMT) has emerged as a discovery in the field of fibrotic disease research. MMT is the process by which macrophages differentiate into myofibroblasts, leading to organ fibrosis following organ damage and playing an important role in fibrosis formation and progression. Recently, many new advances have been made in studying the mechanisms of MMT occurrence in fibrotic diseases. This article reviews some critical recent findings on MMT, including the origin of MMT in myofib… Show more
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