Advances in Imaging Modalities and Contrast Agents for the Early Diagnosis of Colorectal Cancer

Abstract

Colorectal cancer is one of the most common gastrointestinal cancers worldwide. The mortality rate of colorectal cancer has declined by more than 20% due to the rapid development of early diagnostic techniques and effective treatment. At present, there are many diagnostic modalities available for the evaluation of colorectal cancer, such as the carcinoembryonic antigen test, the fecal occult blood test, endoscopy, X-ray barium meal, computed tomography, magnetic resonance imaging, and radionuclide examination. Sensitive and specific imaging modalities have played an increasingly important role in the diagnosis of colorectal cancer following the rapid development of novel contrast agents. This review discusses the applications and challenges of different imaging techniques and contrast agents applied to detect colorectal cancer, for the purpose of the early diagnosis and treatment of patients with colorectal cancer.

Role of empathy in the outcomes of colorectal cancer: protocol for a population-based study in two areas in France (EMPACOL Project)

“…The prognosis of CRC has improved significantly over the past 20 years 1 2. Oncological principles,27 the development of minimally invasive techniques,28 and advances in diagnostic accuracy29 are strongly linked to these outcomes and well described in the recent literature. However, many surviving patients experience functional sequelae (ie, digestive and/or genitourinary sequelae) that significantly impair their QoL.…”

LINC00339 accelerates invasion and migration of colorectal cancer via mediating miRNA-30a-5p

“…There are approximately 3.76 million new cases and 1.91 million death cases of CRC in the Chinese population (4,5). The pathogenesis of CRC involves both genetic and environmental factors (6,7). Although the screening strategies have advanced in recent years, there are still many CRC patients who are diagnosed in the advanced stage due to untimely screening and obscure symptoms 7 .…”