Advances in imaging for pancreatic disease

Frate, Chiara Del; Zanardi, Romeo; Mortelé, Koenraad J.; Ros, Pablo R.

doi:10.1007/s11894-002-0051-x

Cited by 27 publications

(4 citation statements)

References 50 publications

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“…Frate et al 26 stated that MSCT has an accuracy rate for staging of pancreatic adenocarcinoma of virtually 100%. In our study the overall accuracy of tumor staging by MSCT was 84%.…”

Section: Discussionmentioning

confidence: 99%

Current status of multi-detector row helical CT in imaging of adult acquired pancreatic diseases and assessing surgical neoplastic resectability

Tadros

Elia

2017

Alexandria Journal of Medicine

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Background: It is usually hard to detect pancreatic lesions early as the pancreas lays retro peritoneum so it cannot be assessed during a routine physical exam. By the time a person has symptoms, the disease has already established morphological imaging CT changes. Objective: The objective of our study was to clarify the role of multidetector computerized tomography (MDCT) in different adult acquired pancreatic diseases and assess the efficacy of surgical pancreatic tumors resectability preoperative. Materials & methods: The study included thirty adult patients suspected to have pancreatic diseases (18 males and 12 females); their age range was 45-90 years with a mean age of 68 years. All patients underwent triple-phase multi-detector row CT using a 16-slice machine. The presence of inflammation, masses, and vascular invasion was evaluated and interpreted images were obtained during each phase. Results were compared with surgery, histopathology or follow-up. Results: Of 30 patients, 15 had pancreatic malignancies (14 adenocarcinoma of which 6 were resectable and 8 were irresectable, 1 distant metastasis) proven at biopsy and/or surgery, 11 patients had pancreatitis (acute and chronic), three patients had cystic benign tumors (2 mucinous cystadenoma, 1 serous cystadenoma), and one patient had neuroendocrine tumor (insulinoma). Conclusion: Contrast enhanced multiphase pancreatic imaging by MDCT with its post processing techniques represents the imaging modality of choice for the diagnosis of different adult acquired pancreatic diseases.

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“…Frate et al 26 stated that MSCT has an accuracy rate for staging of pancreatic adenocarcinoma of virtually 100%. In our study the overall accuracy of tumor staging by MSCT was 84%.…”

Section: Discussionmentioning

confidence: 99%

Current status of multi-detector row helical CT in imaging of adult acquired pancreatic diseases and assessing surgical neoplastic resectability

Tadros

Elia

2017

Alexandria Journal of Medicine

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“…However, multislice spiral CT (MSCT) with its highly accurate display of anatomic detail has started to challenge the position of MRI [6]. At present, MSCT is generally viewed as the most efficient modality for initial detection and staging of pancreatic carcinoma [7].…”

Section: Introductionmentioning

confidence: 99%

Assessment of vascular invasion in pancreatic head cancer with multislice spiral CT: value of multiplanar reconstructions

et al. 2004

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The use of multiplanar reconstructions (MPRs) generated from multislice spiral CT (MSCT) data sets in the preoperative assessment of vascular invasion in pancreatic cancer was evaluated. Forty patients underwent biphasic high-resolution MSCT prior to surgery for pancreatic head cancer. Image reconstruction included thin-slice axial, sagittal and coronal MPRs as well as an MPR perpendicular to the course of a major peripancreatic vessel in proximity to the tumor. CT criteria for vascular invasion were: (1) circumferential involvement >180 degrees and (2) vessel narrowing. Imaging findings of 52 vessels were correlated with surgical and histopathological reports. Regarding the CT criterion circumferential involvement, vascular invasion was demonstrated on axial MPRs with a sensitivity and specificity of 58 and 97%. For the assessment with coronal and sagittal MPRs sensitivity was only 47%. Vascular invasion was recognized best on perpendicular MPRs with a sensitivity, specificity and accuracy of 74, 97 and 88%, respectively. Vessel narrowing was a less reliable CT criterion for vascular invasion, mainly due to the lower specificity of 91% obtained with each available MPR. Thin-slice MPRs oriented perpendicularly to a possibly invaded vessel exactly depict the grade of circumferential involvement and thus have the capability to improve the assessment of vascular invasion in pancreatic cancer.

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“…EUS is superior to CT in the detection of pancreatic tumors especially with a diameter of less than 25 mm [13]- [15]. Recently, however, with the advent of MDCT (multidetector CT), this difference has reduced [16] [17]. EUS can also locate lymph node metastasis and vascular infiltration with a higher sensitivity than CT [18].…”

Section: Linear Endoscopic Ultrasound 1) Pancreatic Cancermentioning

confidence: 99%

Comparative Study between Endoscopic Ultrasonography and Transabdominal Ultrasonography in the Assessment of Pancreatobiliary Diseases (with Literatures Review)

Alkarboly¹,

Mohammad²,

Hussein³

et al. 2016

OJGas

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Background: Endoscopic ultrasonography (EUS) and transadominal ultrasonography (TUS) are two imaging investigations which can be used to assess pancreatobiliary status, although both of these imaging techniques are operator and machine dependent, but they have different sensitivity and specificity in detecting pancreatobiliary diseases. Objective: To compare the diagnostic value of EUS versus TUS in the assessment of pancreatobiliary diseases. Patients and Methods: This study was conducted in KCGH (Kurdistan Center for Gastroenterology and Hepatology) in Sulaimani city. Iraqi Kurdistan; the duration of study was 14 months and conducted after approval of Iraqi board ethical committee. One hundred cases were enrolled in the study: 52 of them were females and 48 were males; their ages ranged between 16-90 years; informed consent was taken from all patients; all patients underwent proper clinical evaluation; TUS, EUS and Oesophagogastroduodenoscopy (OGD), and in some of them (25 patients) Endoscopic Retrograde Cholangiopancreatography (ERCP), CT scan of abdomen and laboratory investigations were done. Results: EUS detected more cases with common bile duct (CBD) dilatation, CBD stones and pancreatic space occupying lesion (SOL) than TUS, but the differences in the results were not statistically significant. Also EUS detected more cases of intra-abdominal lymph nodes (LNs) and ampullary/peri-ampullary neoplasms than TUS and the differences in the results were statistically significant. Conclusions: Eus is more sensitive than TUS in diagnosing CBD dilatation; it has higher sensitivity than TUS in suspected pancreatobiliary neoplasms; furthermore, EUS can be used for staging and resectability assessment of pancreatobiliary neoplasia.

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Advances in imaging for pancreatic disease

Cited by 27 publications

References 50 publications

Current status of multi-detector row helical CT in imaging of adult acquired pancreatic diseases and assessing surgical neoplastic resectability

Current status of multi-detector row helical CT in imaging of adult acquired pancreatic diseases and assessing surgical neoplastic resectability

Assessment of vascular invasion in pancreatic head cancer with multislice spiral CT: value of multiplanar reconstructions

Comparative Study between Endoscopic Ultrasonography and Transabdominal Ultrasonography in the Assessment of Pancreatobiliary Diseases (with Literatures Review)

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