Advances in Drug Testing for Substance Abuse Alternative Programs

Jones, Joseph

doi:10.1016/s2155-8256(16)31009-2

Cited by 6 publications

(14 citation statements)

References 26 publications

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“…The professional activities of scientists and medical professionals within the field of toxicology fall into four main branches namely; forensic, industrial, clinical and environmental toxicology. Forensic toxicology is mainly concerned with the determination of the presence or absence and role of alcohol, drugs and their metabolites as well as other toxic substances in biological fluids, and/or tissues to solve a medico legal problem [5].…”

Section: Main Branches Of Toxicologymentioning

confidence: 99%

“…Using highly specialized tests, methodologies and state-of-the-art equipment, chemical and biomedical instrumentation and chemical reagents, forensic toxicologists are requested to determine either the presence or the absence of chemicals while documenting each step of the process, and to determine the concentration of any detected substance to help finding out whether or not such xenobiotic was a cause of an unexplained death, accident or act [5].…”

Section: Main Branches Of Toxicologymentioning

confidence: 99%

“…The conformity of a forensic toxicology laboratory with acknowledged quality and management structures is currently mandated in many countries, to be able to accept their analytical results and reports. As there are an essentially unlimited number of poisons that may be present in individual cases, therefore forensic toxicology is a scientific discipline in which everlasting efforts should be constantly exerted to complete and improve the methods of poison detection and show its close relation to raising quality [4][5][6].…”

Section: Main Branches Of Toxicologymentioning

confidence: 99%

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Forensic Toxicology

Issa¹

2019

Poisoning in the Modern World - New Tricks for an Old Dog?

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Forensic toxicology is a broad science that integrates principles and practices about toxicology and legal aspects, which occur in conjunction with medicolegal instances as with homicide, suicide, road traffic and other types of accident and/ or disasters. Nowadays, the practitioners of forensic toxicology science have to deal with three chief sections, namely: postmortem, drug testing, and human performance forensic toxicology. Postmortem forensic toxicology is dealing mostly with investigation of abnormal deaths, or when drug intoxication incidence is assumed as a cause of death and no abnormal findings were detected during autopsy.

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Section: Main Branches Of Toxicologymentioning

confidence: 99%

Section: Main Branches Of Toxicologymentioning

confidence: 99%

Section: Main Branches Of Toxicologymentioning

confidence: 99%

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Forensic Toxicology

Issa¹

2019

Poisoning in the Modern World - New Tricks for an Old Dog?

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“…Therefore, by analysing these types of drugs, the law enforcement can pursue criminal charges and the court can determine appropriate sentencing against the suspected individual (Llah et al, 2016). Moreover, illicit drugs can be classified in to different types as shown in table 1, causing behavioural changes in the individual by acting on the central nervous system (CNS) due to prolonged usage of the drug (Jones, 2016). (Jones, 2016).…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, illicit drugs can be classified in to different types as shown in table 1, causing behavioural changes in the individual by acting on the central nervous system (CNS) due to prolonged usage of the drug (Jones, 2016). (Jones, 2016).…”

Section: Introductionmentioning

confidence: 99%

Recent Advancement in Forensic Toxic Drug Analysis by Desorption Electrospray Ionization Mass Spectrometry (Desi-Ms)

Ahmed¹,

Kandiah²

2017

International Conference on Bioscience and Biotechnology

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Forensic toxicology is the analysis of biological samples to identify the presence of any harmful substances in the body. The three major sub disciplines in forensic toxicology are; human performance toxicology, post-mortem toxicology and forensic drug analysis. Hence, from the three major sub disciplines in forensic toxicology, forensic drug analysis is of major interest, as it involves in the identification of illicit and counterfeit pharmaceutical drugs in biological matrices.Thus, desorption electrospray ionization mass spectrometry (DESI-MS) is an emerging technique in rapid analysis of biological samples in forensic drug analysis, due to the increase in illicit and counterfeit drug users during the past decade. Although, this technique allows the direct analysis of samples from the surface at ambient pressure, development in the technique has been made to increase the sensitivity and specificity in analysing forensic drugs. Meanwhile, improvements in the extraction procedures prior to DESI-MS analysis, possibilities in analysing the drugs in raw urine sample from its native environment and reduction in the geometrical parameters have been the major developments made in DESI-MS. Also, advancement in DESI-MS enables direct analysis of drug tablets to identify the active pharmaceutical drugs present in the tablet and distinguishes between pharmaceutical drugs and counterfeit or fake drugs. This safety evaluation is important as several counterfeit drugs are prepared with illicit components and sold in the market and used to perform illegal activities. Therefore, the recent advancement in forensic toxic drug analysis by DESI-MS enables the law enforcement to pursue criminal charges against the suspect.

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Appropriate Use of Drug Testing in Clinical Addiction Medicine

2017

Journal of Addiction Medicine

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Advances in Drug Testing for Substance Abuse Alternative Programs

Cited by 6 publications

References 26 publications

Forensic Toxicology

Forensic Toxicology

Recent Advancement in Forensic Toxic Drug Analysis by Desorption Electrospray Ionization Mass Spectrometry (Desi-Ms)

Appropriate Use of Drug Testing in Clinical Addiction Medicine

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