Advances in diffuse malignant peritoneal mesothelioma

Yan, Tristan D.; Hassan, Raffit; Welch, Laura S.; Sugarbaker, Paul H.

doi:10.1007/s12156-007-0007-3

Cited by 5 publications

(2 citation statements)

References 69 publications

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“…Previously, DMPM was treated with a combination of systemic chemotherapy, palliative surgery, and, in a few patients, total abdominal radiation capable of achieving a median survival of 12 months [14]. Prognosis of DMPM is poor, with a median survival rate of <1 year [6,15]. However, new therapeutic strategies (e.g., combined approach with cytoreduction surgery and hyperthermic intraperitoneal chemotherapy) have prolonged survival considerably in selected cases in recent years [6,14].…”

Section: Discussionmentioning

confidence: 99%

Diffuse malignant peritoneal mesothelioma

Shih

Tsay

et al. 2013

The Kaohsiung J of Med Scie

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Mesothelioma often originates in the pleura and less frequently in the peritoneum. This article describes a rare case of diffuse malignant peritoneal mesothelioma in a 54-year-old male construction worker who was admitted to our hospital with a 2-month history of progressive abdominal distention. Abdominal computed tomography revealed extensive peritoneal nodularity and omental cake along with massive ascites. Imaging findings initially suggested peritoneal carcinomatosis, primary peritoneal carcinoma, and tuberculous peritonitis. Laparoscopic biopsy of the omentum and peritoneum confirmed the diagnosis of malignant peritoneal mesothelioma of epitheloid type. Although systemic chemotherapy was administered, no tumor regression was found. The patient finally died of nosocomial infection.

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Section: Discussionmentioning

confidence: 99%

Diffuse malignant peritoneal mesothelioma

Shih

Tsay

et al. 2013

The Kaohsiung J of Med Scie

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“… [4] However, the prognosis of malignant peritoneal mesothelioma remains poor, with a median survival of <1 year. [5] A new clinical classification of malignant peritoneal mesothelioma, based on the clinical presentation, into 3 clinical types (classic, medical, and surgical) is characterized by the clinical course of the tumor. [6] We report a case of medical-type peritoneal mesothelioma leading to death 2 months after the onset of fever of unknown origin, along with a review of the literature.…”

Section: Introductionmentioning

confidence: 99%

Medical-type peritoneal mesothelioma leading to death two months after onset of fever of unknown origin

Ishizuka

Uehara

Arai

et al. 2022

Radiology Case Reports

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In malignant mesotheliomas, cases involving the peritoneum as the primary site are rare, accounting for approximately 10% of all mesothelioma cases. We report a case of medical-type peritoneal mesothelioma leading to death 2 months after the onset of fever of unknown origin, along with a review of the literature. A 76-year-old man presented with a fever of unknown origin over 4 weeks. Thoracoabdominal computed tomography (CT) scan showed increased mesenteric adipose tissue density. 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) scan showed diffuse hyperaccumulation in the mesentery and hyperaccumulation in the intraperitoneal and parasternal lymph nodes. A thoracoscopic biopsy of the parasternal lymph nodes revealed metastatic peritoneal mesothelioma. The treatment plan was discussed with him and his family, and the best supportive care was provided. 2 months later, he died from multiple organ failure. Underlying malignant tumors cause 38% of mesenteric panniculitis cases. Symptoms accompanied by lymphadenopathy within the area of mesenteric panniculitis are highly suggestive of malignancy. Peritoneal mesothelioma can be classified as (1) classical, which is accompanied by abdominal pain, ascites, and abdominal masses; (2) surgical, which is accompanied by hernia incarceration and intestinal occlusion; and (3) medical, wherein systemic symptoms, such as fever and weight loss, are primarily observed. The medical-type peritoneal mesothelioma, wherein systemic symptoms are primarily observed, has a poorer prognosis than the other types. FDG-PET/CT is an effective diagnostic modality for peritoneal mesothelioma and typically shows diffuse hyperaccumulation along the peritoneal surface.

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Peritonectomy of the colonic mesentery. Case report of a new surgical technology

Sugarbaker¹

2021

International Journal of Surgery Case Reports

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Introduction and importance Malignant peritoneal mesothelioma is a local-regional disease process that requires a comprehensive treatment plan including complete cytoreductive surgery and regional chemotherapy. Case presentation Treatments used in our patient began with a complete cytoreductive surgery. This required visceral resections, parietal peritonectomy, peritonectomy of the small bowel and its mesentery, and a peritoneal resection of the colonic mesentery with sparing of the major vasculature of the large bowel. Clinical discussion Peritoneal resection of the colonic mesentery and other treatments were performed in the absence of major complications. A 20-day hospitalization was required. The patient shows no internal hernias and no evidence of disease by CT follow-up at 4 years postoperatively. Her quality of life is excellent. Conclusions Malignant peritoneal mesothelioma was in the past a disease of limited survival without effective treatment options. Peritoneal resection of the colonic mesentery may be required for complete cytoreduction. A sequence of cytoreductive surgical procedures and regional chemotherapy treatments has made long-term survival possible.

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Advances in diffuse malignant peritoneal mesothelioma

Cited by 5 publications

References 69 publications

Diffuse malignant peritoneal mesothelioma

Diffuse malignant peritoneal mesothelioma

Medical-type peritoneal mesothelioma leading to death two months after onset of fever of unknown origin

Peritonectomy of the colonic mesentery. Case report of a new surgical technology

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