2022
DOI: 10.3390/molecules27031058
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Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix

Abstract: Astragali Radix (AR) is one of the well-known traditional Chinese medicines with a long history of medical use and a wide range of clinical applications. AR contains a variety of chemical constituents which can be classified into the following categories: polysaccharides, saponins, flavonoids, amino acids, and trace elements. There are several techniques to extract these constituents, of which microwave-assisted, enzymatic, aqueous, ultrasonic and reflux extraction are the most used. Several methods such as sp… Show more

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Cited by 27 publications
(14 citation statements)
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“…Nowadays, HQ is used extensively in clinical therapy, such as in Huangqi injections for treating renal diseases. 28 HJ has a long history with many chemical components with anticancer, antiaging, antidiabetes, and antifatigue properties. 29 RCR contains various bioactive compounds, such as phenylethanoid glycosides, flavonoids, lignin, and alkaloids, with potent antioxidant properties with the capability to improve mitochondrial function, 30,31 and displaying a range of functions, including antioxidant, antinociceptive, anti-inflammatory, and immunity.…”
Section: Discussionmentioning
confidence: 99%
“…Nowadays, HQ is used extensively in clinical therapy, such as in Huangqi injections for treating renal diseases. 28 HJ has a long history with many chemical components with anticancer, antiaging, antidiabetes, and antifatigue properties. 29 RCR contains various bioactive compounds, such as phenylethanoid glycosides, flavonoids, lignin, and alkaloids, with potent antioxidant properties with the capability to improve mitochondrial function, 30,31 and displaying a range of functions, including antioxidant, antinociceptive, anti-inflammatory, and immunity.…”
Section: Discussionmentioning
confidence: 99%
“…The Chinese herbs Radix Astragali Mongolici (Huangqi), the dried root of leguminous plants Mongolia, is widely prescribed to treat cardiovascular disorders, hepatitis, kidney disease, and skin diseases in China [ 67 , 68 ]. Astragaloside IV, a tetracyclic triterpenoid saponin, has been identified as one of the bioactive ingredients in Huangqi [ 67 ].…”
Section: Potential Therapeutic Effects Of Tcm Active Ingredients In Taomentioning
confidence: 99%
“…Commonly used extraction methods for plant compounds include impregnation, distillation, Soxhlet extraction, ultrasonic-assisted extraction, and microwave-assisted extraction. The selection of the appropriate extraction method can aid the extraction of the stable specified compounds and obtain many such compounds for research purposes ( Idris and Mohd Nadzir, 2021 ; Chang et al, 2022 ). The protection of plant resources is a problem that requires considerable attention.…”
Section: Critical Considerationsmentioning
confidence: 99%