Advances in characterization of probiotics and challenges in industrial application

Ranjan, Anuj; Arora, Jayati; Chauhan, Abhishek; Basniwal, Rupesh Kumar; Kumari, Arpna; Rajput, Vishnu D.; Празднова, Е. В.; Ghosh, Arabinda; Mukerjee, Nobendu; Mandzhieva, Saglara; Sushkova, Svetlana; Minkina, Tatiana; Jindal, Tanu

doi:10.1080/02648725.2022.2122287

Cited by 4 publications

(2 citation statements)

References 249 publications

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“…Finally, the stability and shelf life of probiotics are also a challenge. The probiotic strains should maintain their viability and functional characteristics during storage and distribution [ 43 , 44 ].…”

Section: Production Challenges For the Ngpsmentioning

confidence: 99%

Next-Generation Probiotics as Novel Therapeutics for Improving Human Health: Current Trends and Future Perspectives

Abouelela,

Helmy

2024

Microorganisms

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Next-generation probiotics (NGPs) represent an innovative group of beneficial bacteria that are currently undergoing research and development. NGPs are designed not only for conventional use as foods or dietary supplements but are also tailored for pharmaceutical applications. Research indicates that NGPs show therapeutic promise in addressing various chronic ailments. Offering multiple advantages over conventional probiotics, NGPs present opportunities for personalized probiotic therapies, involvement in synthetic biology and gene editing, participation in combination therapies, targeted delivery methods, and application in therapeutic settings. Our review discusses the potential therapeutic effect of the NGPs, covering diverse research trajectories for NGPs, including their identification, characterization, and targeted delivery. Furthermore, this review elucidates the influence of NGPs on critical aspects of human health, specifically, gut health, immune function, and broader health outcomes. Mechanistic insights encompass the production of bioactive compounds, competitive interactions with pathogenic bacteria, the modulation of immune cell activity, and the reinforcement of the gut barrier. What is noteworthy is that the current review points out the prevalent NGP strains and their diverse sources, providing a highlight for the comprehensive framework for understanding their potential applications and their future benefits in the domain of advanced therapeutics.

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Section: Production Challenges For the Ngpsmentioning

confidence: 99%

Next-Generation Probiotics as Novel Therapeutics for Improving Human Health: Current Trends and Future Perspectives

Abouelela,

Helmy

2024

Microorganisms

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“…Organophosphates (OP) are chemical substances produced by the process of esterification between phosphoric acid and alcohol. These chemicals are the main components of herbicides, pesticides, and insecticides [ 6 ]. Organophosphate poisoning can be acute or chronic.…”

Section: Introductionmentioning

confidence: 99%

Green Spectrophotometric Determination of Organophosphate in Selected Fruits and Vegetables

Sharma

Sapkota

Paudel

et al. 2023

International Journal of Analytical Chemistry

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A simple, sensitive, precise, and environmentally safe spectrophotometry method was developed and validated for the determination of organophosphate in various fruits and vegetables using a UV-Visible spectrophotometer using a magnesia mixture. The volume of reagent used for analysis and the stability of the color complex were also optimized. The drug showed a stable white color complex at 420 nm. The greenness of the methods was estimated using an ecoscale (84), the Green Analytical Procedure Index, and AGREE (0.89), which were found to be excellent green method based on spectrophotometric determination. The method was validated using ICH guidelines and has acceptable values for linearity (0.5–2.5 mg/ml), accuracy (98.5–102.5%), precision, robustness, limit of detection (0.16 mg), and limit of quantification (0.486 mg). The concentration of the organophosphate in the analyzed sample was in the range of 0.003 to 2.45 mg. Altogether, the proposed green analytical method was found to be a simple, selective, sensitive, accurate, and ecofriendly method for the analysis of organophosphate in various fruits and vegetables.

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Challenges in maintaining the probiotic potential in alcoholic beverage development

et al. 2023

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Advances in characterization of probiotics and challenges in industrial application

Cited by 4 publications

References 249 publications

Next-Generation Probiotics as Novel Therapeutics for Improving Human Health: Current Trends and Future Perspectives

Next-Generation Probiotics as Novel Therapeutics for Improving Human Health: Current Trends and Future Perspectives

Green Spectrophotometric Determination of Organophosphate in Selected Fruits and Vegetables

Challenges in maintaining the probiotic potential in alcoholic beverage development

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