Advancements in Schiff Bases of 1H-Indole-2,3dione: A Versatile Heterocyclic Compound in Pharmacological Field

Abstract

Heterocyclic compounds have specific structural peculiarities which impart immense applications in various fields. Here, we have explored the medicative importance of a captive heterocyclic compound, 1H-Indole-2,3dione, commonly known as Isatin. The flexibility in the structure of isatin makes it more innovative to have applications in the biological and analytical fields. In this mini-review, we have intensified about the Schiff bases of isatin in various activities like antidiabetic, antioxidant and also the importance of this compound in the development of anticancer as well as antidiabetic, antimalarial, antiviral, anticonvulsant, anti-inflammatory and analgesic activity based on the reports mainly focussed on the current and past couple of years.