Advancement of chitin and chitosan as promising biomaterials

Al‐Rooqi, Munirah M.; Hassan, M. Masudul; Moussa, Ziad; Obaid, Rami J.; Suman, Nahid Hasan; Wagner, Manfred H.; Natto, Sameer S. A.; Ahmed, Saleh A.

doi:10.1016/j.jscs.2022.101561

Cited by 37 publications

(24 citation statements)

References 106 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chitosan (a polysaccharide derived from chitin) was chosen for this purpose. Apart from the fact that this natural polymer possesses, among others, attractive attributes such as biocompatibility, biodegradability, untoxicity, and antitumor, analgesic, antioxidant, and antimicrobial properties [ 56 ], it is known for its ability to form hydrogels.…”

Section: Resultsmentioning

confidence: 99%

Performance of Dye Removal from Single and Binary Component Systems by Adsorption on Composite Hydrogel Beads Derived from Fruits Wastes Entrapped in Natural Polymeric Matrix

Grigoraș

Simion

Favier

et al. 2022

Gels

View full text Add to dashboard Cite

The treatment of contaminated water is currently a major concern worldwide. This work was directed towards the preparation of a composite hydrogel by entrapping cherry stones powder on chitosan, which is known as one of the most abundant natural polymers. The synthesized material was characterized by scanning electron microscopy, by Fourier transform infrared spectroscopy, and by the point of zero charge determination. Its ability to remove two azo dyes models (Acid Red 66 and Reactive Black 5) existing in single form and in binary mixture was evaluated. Response Surface Methodology–Central Composite Design was used to optimize three parameters affecting the process while targeting the lowest final contaminant concentrations. The best results were obtained at pH 2, an adsorbent dose of 100 g/L, and a temperature of 30 °C, when more than 90% of the pollutants from the single component systems and more than 70% of those of the binary mixtures were removed from their aqueous solutions. The adsorption process was in accordance with Elovich and pseudo-second-order kinetic models, and closely followed the Freundlich and Temkin equilibrium isotherms. The obtained results led to the conclusion that the prepared hydrogel composite possesses the ability to successfully retain the target molecules and that it can be considered as a viable adsorbent material.

show abstract

Section: Resultsmentioning

confidence: 99%

Performance of Dye Removal from Single and Binary Component Systems by Adsorption on Composite Hydrogel Beads Derived from Fruits Wastes Entrapped in Natural Polymeric Matrix

Grigoraș

Simion

Favier

et al. 2022

Gels

View full text Add to dashboard Cite

show abstract

“…Chitosan is a deacetylated process derived from chitin, and consists of D-glucosamine and N-acetyl-D-glucosamine units linked to β-(1→4) [ 57 , 58 ]. Its cationic property, which enhances adhesion through electrostatic interactions to negatively charged mucosal surfaces, is one of the most significant characteristics of chitosan; it results in increased drug internalization in target cells [ 59 , 60 , 61 ].…”

Section: Chitosan-based Nanosystem Of Smart Drug Delivery Systemmentioning

confidence: 99%

Chitosan-Based Nano-Smart Drug Delivery System in Breast Cancer Therapy

et al. 2023

View full text Add to dashboard Cite

Despite recent advances, cancer remains the primary killer on a global scale. Numerous forms of research have been conducted to discover novel and efficient anticancer medications. The complexity of breast cancer is a major challenge which is coupled with patient-to-patient variations and heterogeneity between cells within the tumor. Revolutionary drug delivery is expected to provide a solution to that challenge. Chitosan nanoparticles (CSNPs) have prospects as a revolutionary delivery system capable of enhancing anticancer drug activity and reducing negative impacts on normal cells. The use of smart drug delivery systems (SDDs) as delivering materials to improve the bioactivity of NPs and to understand the intricacies of breast cancer has garnered significant interest. There are many reviews about CSNPs that present various points of view, but they have not yet described a series in cancer therapy from cell uptake to cell death. With this description, we will provide a more complete picture for designing preparations for SDDs. This review describes CSNPs as SDDSs, enhancing cancer therapy targeting and stimulus response using their anticancer mechanism. Multimodal chitosan SDDs as targeting and stimulus response medication delivery will improve therapeutic results.

show abstract

“…On the other hand, chitin, a polymer composed of N -acetylglucosamine (β-1,4-linked 2-acetamido- d -glucose), is the most abundant aminopolysaccharide found in nature, primarily in crustaceans, mollusks, insects, and fungi. , There are three chitin allomorphs (α-chitin, β-chitin, γ-chitin) with different structural and mechanical properties. , While α-chitin is primarily found in shells and stiff materials, β-chitin and γ-chitin are mostly found in soft and flexible structures . These structural and mechanical variations are attributed to the different arrangements of polysaccharide chains; α-chitin chains align antiparallel to the reducing end, β-chitin chains are parallel, and γ-chitin chains feature a combination of parallel and antiparallel arrangements. , Chitin accounts for approximately 15–40% of the 6–8 million tons of annually produced waste shells from crustaceans such as lobsters, shrimp, and crabs. , Most of this waste is disposed of into the sea, leading to marine environmental pollution and consequent deterioration in affected ecosystems .…”

Section: Introductionmentioning

confidence: 99%

“…14,17 On the other hand, chitin, a polymer composed of Nacetylglucosamine (β-1,4-linked 2-acetamido-D-glucose), is the most abundant aminopolysaccharide found in nature, primarily in crustaceans, mollusks, insects, and fungi. 18,19 There are three chitin allomorphs (α-chitin, β-chitin, γ-chitin) with different structural and mechanical properties. 19,20 While α-chitin is primarily found in shells and stiff materials, β-chitin and γ-chitin are mostly found in soft and flexible structures.…”

Section: Introductionmentioning

confidence: 99%

Hybrid Amyloid–Chitin Nanofibrils for Magnetic and Catalytic Aerogels

Peydayesh,

Boschi,

Bagnani

et al. 2024

ACS Nano

View full text Add to dashboard Cite

In the quest for a sustainable and circular economy, it is essential to explore environmentally friendly alternatives to traditional petroleum-based materials. A promising pathway toward this goal lies in the leveraging of biopolymers derived from food waste, such as proteins and polysaccharides, to develop advanced sustainable materials. Here, we design versatile hybrid materials by hybridizing amyloid nanofibrils derived by selfassembly of whey, a dairy byproduct, with chitin nanofibrils exfoliated from the two distinct allomorphs of α-chitin and βchitin, extracted from seafood waste. Various hydrogels and aerogels were developed via the hybridization and reassembly of these biopolymeric nanobuilding blocks, and they were further magnetized upon biomineralization with iron nanoparticles. The pH-phase diagram highlights the significant role of electrostatic interactions in gel formation, between positively charged amyloid fibrils and negatively charged chitin nanofibrils. Hybrid magnetic aerogels exhibit a ferromagnetic response characterized by a low coercivity (<50 Oe) and a high specific magnetization (>40 emu/g) at all temperatures, making them particularly suitable for superparamagnetic applications. Additionally, these aerogels exhibit a distinct magnetic transition, featuring a higher blocking temperature (200 K) compared to previously reported similar nanoparticles (160 K), indicating enhanced magnetic stability at elevated temperatures. Finally, we demonstrate the practical application of these hybrid magnetic materials as catalysts for carbon monoxide oxidation, showcasing their potential in environmental pollution control and highlighting their versatility as catalyst supports.

show abstract

Advancement of chitin and chitosan as promising biomaterials

Cited by 37 publications

References 106 publications

Performance of Dye Removal from Single and Binary Component Systems by Adsorption on Composite Hydrogel Beads Derived from Fruits Wastes Entrapped in Natural Polymeric Matrix

Performance of Dye Removal from Single and Binary Component Systems by Adsorption on Composite Hydrogel Beads Derived from Fruits Wastes Entrapped in Natural Polymeric Matrix

Chitosan-Based Nano-Smart Drug Delivery System in Breast Cancer Therapy

Hybrid Amyloid–Chitin Nanofibrils for Magnetic and Catalytic Aerogels

Contact Info

Product

Resources

About