Advancement in Borrelia burgdorferi Antibody Testing: Comparative Immunoblot Assay (COMPASS)

Lakos, András; Igari, Erzsébet

doi:10.5772/32724

Cited by 3 publications

(2 citation statements)

References 48 publications

(43 reference statements)

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“…The PTLDS can be signalized if symptoms associated with Borrelia infection are persistent, and last longer than 6 months after treatment. According to the guidelines, this condition does not justify the use of antibiotics, which is referred as useless and potentially harmful to the patient with PTLDS (Lakos, 2012, CDC, 2011. Then the medical and laboratory activities should be focused on assessing the effectiveness of treatment, exclusion of possible failure of therapy or taking into account other factor which is not related to Borrelia infection (Lakos, 2012, CDC, 2011.…”

Section: Discussionmentioning

confidence: 99%

The Analysis of Specific Immune Response for Borrelia Burgdorferi According to in Vivo Antigens in Regard to Symptoms Subiectively Perceived by Foresters

Tokarska-Rodak¹,

Kozioł-Montewka²,

Plewik³

et al. 2014

hpc

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Section: Discussionmentioning

confidence: 99%

The Analysis of Specific Immune Response for Borrelia Burgdorferi According to in Vivo Antigens in Regard to Symptoms Subiectively Perceived by Foresters

Tokarska-Rodak¹,

Kozioł-Montewka²,

Plewik³

et al. 2014

hpc

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“…Approximately 10-20% of patients diagnosed with Lyme disease have non-speci ic clinical symptoms despite use of long antibiotic treatment (Lakos et al 2012). This aspect should be considered in the context of (PTLDS).…”

Section: Lyme Disease -New Infections and Their Relationship With Ecomentioning

confidence: 99%

Current Infectious Threats Associated With the Development of Civilization and Progress in Medicine - Methods of Prevention and Education

Kozioł-Montewka¹,

Pańczuk²,

Tokarska-Rodak³

et al. 2014

hpc

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Summary:The development of civilization, economic growth, urbanization, industrialization and progress in medicine bring to the society an improvement in the quality of life, but at the same time caused changes in lifestyle, environmental conditions, and changes in the natural environment. All of these led to develop civilization diseases which have critical impact and the adverse effect on our health, about what we not always realize. In the past ifty years, about 30 new pathogens appeared causing diseases such as legionellosis, Lyme disease, and increase unexpectedly tuberculosis incidence which in some regions is associated with HIV infections. Also widespread use of antibiotics caused and still causing bacterial resistance increase to most of them. With the development of medicine and surgery, parallel effects of surgical areas and infections associated with implanted cardiac devices in the majority of the life-saving ones appeared. The development of research techniques allowed for the inding of new relationships between ecosystems in the microbiome of the gastrointestinal tract with of obesity in the society. The presence of new health aspects of civilization diseases impose pressure to create new prevention methods and public education.Keywords: Lyme disease, legionellosis, tuberculosis, microbiome, antibiotic resistance Civilization human health was changing over the centuries as a response to the processes of urbanization, industrialization and environmental change. It was related with development and size of infections epidemics, and mortality. During that time we observed progress in medical knowledge, prevention methods, and generally accepted public health status. Traces of the effects of infection are visible in prehistoric anthropological research, and they concern tuberculosis changes in bones, smallpox. The irst mention of the epidemic was recorded in the ifth century BC, and its direct cause was crowding inhabitants and troops within the area of Athens. Mortality rate was high, and the main reason for that was the lack of awareness of proper hygiene. In the Middle were great epidemics of smallpox, plague, cholera, in luenza which destroyed entire cities and the states. They were largely caused by overcrowding of cities and increased migration of the population. In the subsequent centuries the scale of infectious diseases was modi ied by the process of urbanization development of industry (late nineteenth and twentieth century). Progress of microbiological knowledge fallowed by discoveries of Louis Pasteur, Robert Koch and Ilya Mechnikov. The irst preventive vaccinations against smallpox were introduced thanks to the observations of Edward Jenner in the eighteenth century.Modern civilization is still not free from infectious diseases in spite of signi icant progress in medicine economic, and social achievements. We observe important changes in the pro ile of infections, prevention methods, species of pathogenic microorganisms and their sensitivity to antibiotics. At the end of the twentieth cent...

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Recent lesson from a clinical and seroepidemiological survey: low positive predictive value of Borrelia burgdorferi antibody testing in a high risk population

Lakos¹,

Igari

Solymosi

2012

Advances in Medical Sciences

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Advancement in Borrelia burgdorferi Antibody Testing: Comparative Immunoblot Assay (COMPASS)

Cited by 3 publications

References 48 publications

The Analysis of Specific Immune Response for Borrelia Burgdorferi According to in Vivo Antigens in Regard to Symptoms Subiectively Perceived by Foresters

The Analysis of Specific Immune Response for Borrelia Burgdorferi According to in Vivo Antigens in Regard to Symptoms Subiectively Perceived by Foresters

Current Infectious Threats Associated With the Development of Civilization and Progress in Medicine - Methods of Prevention and Education

Recent lesson from a clinical and seroepidemiological survey: low positive predictive value of Borrelia burgdorferi antibody testing in a high risk population

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