The growing need for accurate estimation of b By fitting attery's thermal and electrical performances at different operating conditions are crucial in its applications especially in electrified vehicles. This paper presents an effective method for developing a thermal and electrical modelling methodology for calculation thermal behavior of a lithium-ion (Li-ion) cell and the voltage response under a current solicitation. The model was elaborated on three pouch cells with different battery chemistries for use in electrical vehicles/hybrid electrical vehicles, namely: lithium iron phosphate (LFP), lithium nickel manganese cobalt oxide (NMC) and lithium titanium oxide (LTO). The model, implemented in a Matlab/Simulink interface, uses an equivalent circuit and heat generation equations coupled a thermal model. The three cell chemistries have been investigated using test procedures and thermal images at room temperature. The results of this study show that a temperature distribution to be fairly uniform after a complete discharge for the three chemistries with the lowest temperature gradient found for the LTO-based cell. Finally, comparison between simulation results and measured data under a dynamic profiles shows a good correspondence with the measurements of the validation tests with errors lying between ±4% and 2°C for the electrical and thermal model, respectively.