Advanced renal cell carcinoma in Australia, 2015: What should we do?

Davis, Ian D.

doi:10.1111/ajco.12314

Cited by 1 publication

(1 citation statement)

References 15 publications

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“…Renal cell carcinoma (RCC) ranks as the most frequent type of all kidney cancers, which represents more than 85% incidence among kidney cancers [ 1 , 2 ]. It is also the ninth most common cancer in developed countries [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Correlation analysis of VHL and Jade-1 gene expression in human renal cell carcinoma

Chen

et al. 2016

Open Medicine

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AbstractObjectiveThe aim of this study was to investigate the correlation of von Hippel-Lindau tumor suppressor (VHL) mRNA expression and jade family PHD finger 1 (Jade-1) gene expression in patients with renal cell carcinoma (RCC). Another aim of this study was to analyze the relationship of these two genes with clinicalpathological features of the RCC patients. Methods: A total of 75 RCC patients who received surgically therapy in our hospital were included. All patients had complete pathological data. The expression of VHL/Jade-1 was determined by real-time polymerase chain reaction (RT-PCR). Results: VHL and Jade-1 were both obviously downregulated in RCC tissues than that of the matched normal tissues, and both negatively correlated with tumor size as well as tumor grade. And we found a fine association of VHL gene expression with Jade-1. Conclusion: VHL/Jade-1 exhibited significantly decreased expression in RCC tissues and was closely related to the clinical prognosis of patients. The finding of VHL expression positively correlated with Jade-1 expression shed light and provided crucial evidence on the connection of VHL protein with Wnt/b-catenin pathway.

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Section: Introductionmentioning

confidence: 99%

Correlation analysis of VHL and Jade-1 gene expression in human renal cell carcinoma

Chen

et al. 2016

Open Medicine

View full text Add to dashboard Cite

show abstract

Advanced renal cell carcinoma in Australia, 2015: What should we do?

Cited by 1 publication

References 15 publications

Correlation analysis of VHL and Jade-1 gene expression in human renal cell carcinoma

Correlation analysis of VHL and Jade-1 gene expression in human renal cell carcinoma

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