Acute care nurse practitioners, prepared as providers for a variety of populations of patients, continue to make substantial contributions to health care. Evidence indicates shorter stays, higher satisfaction among patients, increased work efficiency, and higher quality outcomes when acute care nurse practitioners are part of unit-or service-based provider teams. The Consensus Model for APRN Regulation: Licensure, Accreditation, Certification, and Education outlines detailed guidelines for matching nurse practitioners' education with certification and practice by using a population-focused algorithm. Despite national support for the model, nurse practitioners and employers continue to struggle with finding the right fit. Nurse practitioners often use their interest and previous nursing experience to apply for an available position, and hospitals may not understand preparation or regulations related to matching the appropriate provider to the work environment. In addition, state boards of nursing do not all ascribe to national recommendations. Inconsistencies are also apparent in the details of interpretation of advanced practice nursing roles between states. Despite evidence that supports the success of the acute care nurse practitioner (ACNP), evidence that documents outcomes on the basis of preparation, certification, and nursing experience is lacking. The evolution of the ACNP role, national recommendations, published population-based competencies, and scope of practice strengthen the differentiation of advanced practice registered nurse (APRN) roles, but do not specify hiring guidelines. The following discussion, gleaned from the available publications, attempts to provide assistance for making appropriate hiring decisions and offers insight and guidance for selecting a suitable candidate.