Advanced Particle Therapy Delivery

Kabolizadeh, Peyman; Ding, Xuanfeng; Li, Xiaoqiang

doi:10.1002/9781119707530.ch7

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2024

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“…Recent advancements in beam delivery technology, such as intensity-modulated proton therapy pencil beam scanning (IMPT-PBS), have spotlighted particle therapy in oncology with its potential for improved treatment outcomes and more optimistic prognoses compared to conventional radiotherapy [14]. Nonetheless, uncertainties in the treatment process remain, particularly concerning the calibration of ion beam range within tissues using diagnostic X-ray computed tomography (CT) images.…”

Section: Introductionmentioning

confidence: 99%

Prompt gamma imaging system in particle therapy: a mini-review

Cheon,

Min

2024

Front. Phys.

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Accurate in-vivo verification of beam range and dose distribution is crucial for the safety and effectiveness of particle therapy. Prompt gamma (PG) imaging, as a method for real-time verification, has gained prominence in this area. Currently, several PG imaging systems are under development, including gamma electron vertex imaging (GEVI), the Compton camera, the slit camera, and the multi-array type collimator camera. However, challenges persist in dose prediction accuracy, largely due to patient positioning uncertainty and anatomical changes. Although each system demonstrates potential in verifying PG range, further improvements in detection efficiency, spatial resolution, background reduction, and integration into clinical workflows are essential.

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Section: Introductionmentioning

confidence: 99%