Advanced particle-based velocimetry techniques for microscale flows

Lee, Sang Joon; Kim, Seok

doi:10.1007/s10404-009-0409-6

Cited by 58 publications

(35 citation statements)

References 73 publications

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“…Fluorescent nano/micro beads are typically used as tracers, and a confocal microscope can be used to deduce the velocity distribution in three dimensions [51][52][53][54][55][56][57][58][59]. Evanescent waves generated by total index reflection of a laser can be used to derive the velocity near the liquid/wall interface, within approximately 50 nm, when they are used as the excitation light for the fluorescent tracer particles [60][61][62][63][64].…”

Section: Introductionmentioning

confidence: 99%

Effects of Micromachining Processes on Electro-Osmotic Flow Mobility of Glass Surfaces

et al. 2013

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Silica glass is frequently used as a device material for micro/nano fluidic devices due to its excellent properties, such as transparency and chemical resistance. Wet etching by hydrofluoric acid and dry etching by neutral loop discharge (NLD) plasma etching are currently used to micromachine glass to form micro/nano fluidic channels. Electro-osmotic flow (EOF) is one of the most effective methods to drive liquids into the channels. EOF mobility is affected by a property of the micromachined glass surfaces, which includes surface roughness that is determined by the manufacturing processes. In this paper, we investigate the effect of micromaching processes on the glass surface topography and the EOF mobility. We prepared glass surfaces by either wet etching or by NLD plasma etching, investigated the surface topography using atomic force microscopy, and attempted to correlate it with EOF generated in the micro-channels of the machined glass. Experiments revealed that the EOF mobility strongly depends on the surface roughness, and therefore upon the fabrication process used. A particularly strong dependency was observed when the surface roughness was on the order of the electric double layer thickness or below. We believe that the correlation described in this paper can be of great help in the design of micro/nano fluidic devices.

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Section: Introductionmentioning

confidence: 99%

Effects of Micromachining Processes on Electro-Osmotic Flow Mobility of Glass Surfaces

et al. 2013

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“…It also has good linearity over most of its range, which is much larger than that available with QPD detection. Other 3D tracking methods have used the point spread function [15,16], contrast inversion [17] or digital holography [18]. These techniques obtain good resolution, at the expense of relatively demanding image analysis.…”

Section: D Position Measurementmentioning

confidence: 99%

“…The axial position can therefore be found by tracking an object in 2D in each image and measuring the apparent difference in position. Commercial stereomicroscopes are designed with small angles (around 10 • ) between viewpoints, and as such achieve relatively coarse axial resolution [15]. It is also possible to use two separate microscope objectives [7], however this results in a large optical system and requires special sample cells.…”

Section: D Position Measurementmentioning

confidence: 99%

Particle tracking stereomicroscopy in optical tweezers: Control of trap shape

Bowman¹,

Gibson²,

Padgett³

2010

Opt. Express

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Abstract:We present an optical system capable of generating stereoscopic images to track trapped particles in three dimensions. Two-dimensional particle tracking on each image yields three dimensional position information. Our approach allows the use of a high numerical aperture (NA= 1.3) objective and large separation angle, such that particles can be tracked axially with resolution of 3 nm at 340 Hz. Spatial Light Modulators (SLMs), the diffractive elements used to steer and split laser beams in Holographic Optical Tweezers, are also capable of more general operations. We use one here to vary the ratio of lateral to axial trap stiffness by changing the shape of the beam at the back aperture of the microscope objective. Beams which concentrate their optical power at the extremes of the back aperture give rise to much more efficient axial trapping. The flexibility of using an SLM allows us to create multiple traps with different shapes.

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“…During the last 10 years, the μPIV technique has been used in many research fields, for example, to study electroosmotic, pressure driven and mixed flow in a twin-T microchannel intersection [34], thermal measurement dependent Brownian motion of microparticles [35], investigation of fluid slip mechanisms at wall [36] and in hydrophobic microchannels, internal circulation of aqueous plugs in two phases flow [37], in measurements of beads suspensions in water and human blood, using the red blood cells as a natural particle seeding [38]. A comprehensive review on the μPIV technique can be found in [39] and [40].…”

Section: Micro-particle Image Velocimetrymentioning

confidence: 99%

Recent advances in digital particle image velocimetry methods for flow motion analysis

Nasibov

Baytaroglu

2010

Int. J. Metrol. Qual. Eng.

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Abstract. The advent of charge-coupled devices (CCD) has significantly extended the horizons of full-field measurement methods in many fields of fundamental and applied sciences, including fluid flow dynamics. One of the major applications of imaging sensors in fluid mechanics is the Digital Particle Image Velocimetry (DPIV), which is a non-invasive, full field optical measuring technique. Due to recent advances in image processing methods, and in digital imaging, laser and optics DPIV has become a dominant tool for obtaining velocity information about fluid motion. On the other hand, over the last years, developments in micro-and nanofluidic systems have promised a shrinking of the desktop-sized chemical and biological devices to microscale size, so a detailed investigation of the behaviour of flow inside these microdevices is essential for the optimum design of microsystems, as well as for an understanding of flow dynamics in micron scales. In this work, the advances in visualization and quantitative measurements of flow velocity measurements are reviewed and explained.

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Advanced particle-based velocimetry techniques for microscale flows

Abstract: Recently, microscale flows have been receiving large attention in various research areas.

Cited by 58 publications

References 73 publications

Effects of Micromachining Processes on Electro-Osmotic Flow Mobility of Glass Surfaces

Effects of Micromachining Processes on Electro-Osmotic Flow Mobility of Glass Surfaces

Particle tracking stereomicroscopy in optical tweezers: Control of trap shape

Recent advances in digital particle image velocimetry methods for flow motion analysis

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