Advanced micro-/nanotechnologies for exosome encapsulation and targeting in regenerative medicine

Golroudbari, Hasti Tashak; Banikarimi, Seyedeh Parnian; Ayati, Aryan; Hadizadeh, Alireza; Zavareh, Zahra Khorasani; Hajikhani, Kiana; Heirani‐Tabasi, Asieh; Tafti, Mohsen Ahmadi; Davoodi, Saeed; Tafti, Hossein Ahmadi

doi:10.1007/s10238-023-00993-7

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2023

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“…EXOs are a highly modular and thus flexible system (providing platform and scaffold) for cell-to-cell communication (see Figure 2). As a result, dynamic behavior is a consequence of exosome function [17]. The central issue for a virus is maintaining its DNA or RNA genome and avoiding any loss of information.…”

Section: Introductionmentioning

confidence: 99%

Extracellular Vesicles and Their Membranes: Exosomes vs. Virus-Related Particles

Cortes-Galvez

Dangerfield²,

Metzner³

2023

Membranes

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Cells produce nanosized lipid membrane-enclosed vesicles which play important roles in intercellular communication. Interestingly, a certain type of extracellular vesicle, termed exosomes, share physical, chemical, and biological properties with enveloped virus particles. To date, most similarities have been discovered with lentiviral particles, however, other virus species also frequently interact with exosomes. In this review, we will take a closer look at the similarities and differences between exosomes and enveloped viral particles, with a focus on events taking place at the vesicle or virus membrane. Since these structures present an area with an opportunity for interaction with target cells, this is relevant for basic biology as well as any potential research or medical applications.

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Section: Introductionmentioning

confidence: 99%