Advanced magnetic resonance imaging detects altered placental development in pregnancies affected by congenital heart disease
Daniel Cromb,
Paddy Slator,
Megan Hall
et al.
Abstract:Congenital heart disease (CHD) is the most common congenital malformation and is associated with adverse neurodevelopmental outcomes. The placenta is crucial for healthy fetal development and placental development is altered in pregnancy when the fetus has CHD. This study utilized advanced combined diffusion-relaxation MRI and a data-driven analysis technique to test the hypothesis that placental microstructure and perfusion are altered in CHD-affected pregnancies. 48 participants (36 controls, 12 CHD) underwe… Show more
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