“…More specifically, over the past decades, EUS has evolved from a mere diagnostic to an additional mature therapeutic modality incorporating novel skill sets, evolving techniques, and revolutionary device platforms (e.g., improved tissue sampling tools, lumen-apposing metal stents, and radiofrequency ablation needles). The addition of advanced imaging (e.g., chromoendoscopy, confocal laser endomicroscopy, and artificial intelligence), resection/dissection techniques (e.g., endoscopic mucosal resection, endoscopic submucosal dissection, “third-space endoscopy”), transmural drainage options, and vascular interventions has only expanded the horizon for interventional endoscopists (3–6). The largest and fastest growing integration hereof is currently established in the management of patients with advanced gastrointestinal and biliopancreatic disorders (3–6).…”