Abstract:Diabetes microenvironment will accelerate the accumulation of Advanced glycation end products (AGEs), therefore, AGEs are a signature product in the study of the diabetes microenvironment. Adipose-derived stem cells (ASCs) have poor osteogenesis in the diabetes microenvironment, but the mechanism of the altered osteogenic potential of ASCs has not been elucidated. Bone tissue engineering by ASCs is widely used in the treatment of bone defects with diabetic osteoporosis. Therefore, this study investigated the e… Show more
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