Abstract:Advanced glycation end products (AGEs), the compounds resulting from the
non-enzymatic glycosylation between reducing sugars and proteins, are derived
from food or produced de novo. Over time, more and more endogenous and
exogenous AGEs accumulate in various organs such as the liver, kidneys, muscle,
and bone, threatening human health. Among these organs, bone is most widely
reported. AGEs accumulating in bone r… Show more
High-fat diets (HFDs) predispose to obesity and liver dysfunctions, and α-dicarbonyl compounds (α-DCs) present in highly processed foods are also implicated in relevant pathological processes.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.