Advanced flow cytometry techniques for clinical detection

McFarlin, Brian K.; Bowman, Erin M.

doi:10.1016/j.ymeth.2018.01.016

Cited by 1 publication

(2 citation statements)

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“…Recently, the rapid development of microfluidic technology lights a pathway. Microfluidics is the technology of manipulation of fluid in microchannels with dimensions in the range of tens of micrometers, and it has been expanded rapidly into the field of cell biology and many other fields . In order to overcome the shortcomings of conventional flow cytometers, researches introduce the concept of microfluidics into the flow cytometry, which is called “microfluidic flow cytometry.” In a microfluidic flow cytometer, cells can be confined in micrometer‐sized chambers and channels that are compatible to their intrinsic volume, thus enabling the analysis of single cell with the minimized dilution or buffer solution.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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New advances in microfluidic flow cytometry

Gong

Fan

et al. 2018

Electrophoresis

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In recent years, researchers are paying the increasing attention to the development of portable microfluidic diagnostic devices including microfluidic flow cytometry for the point‐of‐care testing. Microfluidic flow cytometry, where microfluidics and flow cytometry work together to realize novel functionalities on the microchip, provides a powerful tool for measuring the multiple characteristics of biological samples. The development of a portable, low‐cost, and compact flow cytometer can benefit the health care in underserved areas such as Africa or Asia. In this article, we review recent advancements of microfluidics including sample pumping, focusing and sorting, novel detection approaches, and data analysis in the field of flow cytometry. The challenge of microfluidic flow cytometry is also examined briefly.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%