Advanced adenoid cystic carcinoma of the skull base – The role of surgery

Guazzo, Emily; Bowman, James; Porceddu, Sandro; Webb, Lachlan; Panizza, Benedict

doi:10.1016/j.oraloncology.2019.104466

Cited by 11 publications

(14 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ACC can arise in any salivary gland tissue and within the head and neck - the major salivary glands represent the most common site, followed by tumors originating in the sinonasal tract. 9 Giant ACC with osseous invasion has been rarely reported. This is the first case report of giant ACC with jugular foramen destruction mimicking large glomus jugulare in location as well as clinical presentation.…”

Section: Discussionmentioning

confidence: 99%

“…Because of this, surgical procedures frequently result in partial excision, which increases the likelihood of local recurrence. 9,23 Neurosurgeons should keep the patient disability-free if complete resection of the tumor is not possible. However, in patients with established disabilities, the target should be complete resection without leaving any metastatic lymph nodes and without adding any new deficits.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Posterior fossa giant adenoid cystic carcinoma with skull base invasion mimicking glomus jugulare: A case report and review of literature

et al. 2023

View full text Add to dashboard Cite

The author describes a rare case of giant adenoid cystic carcinoma (ACC) mimicking large paraganglioma with lower cranial nerve palsy. A 60-year-old female presented with a progressive increase in postauricular swelling with unilateral hearing loss, facial deviation, difficulty in swallowing, and hoarseness of voice. MRI brain showed highly vascular infiltrating and osteolytic mass suggestive of large glomus jugulare versus sarcoma. It was completely engulfing the jugular foramen and lower cranial nerves with bony erosion of the jugular foramen and occipital condyle. The whole mastoid was filled with the tumor. On digital subtraction angiography the majority of blood supply was from the occipital branch of the external carotid artery and vertebral artery. The patient underwent percutaneous embolization followed by external carotid ligation and resection of the mass. The postoperative course was uneventful. Histopathology was suggestive of mixed ACCs. The patient received radiotherapy. After 1 year of follow up no recurrence or distant metastasis was noted.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Posterior fossa giant adenoid cystic carcinoma with skull base invasion mimicking glomus jugulare: A case report and review of literature

et al. 2023

View full text Add to dashboard Cite

show abstract

“…The usual treatment is complete tumor resection to negative histological margins combined with postoperative radiotherapy. Such therapy allows a 10-year local regional disease control rate of 88.2% compared with 36% using radiotherapy alone [ 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

Adenoid cystic carcinoma of jugular foramen

Mahéo

Abgrall

Conan

et al. 2022

Radiology Case Reports

View full text Add to dashboard Cite

“…Regardless of the primary tumor site, surgery is the standard of care for non-metastatic ACC. The primary goal is a complete surgical excision ( 10 ). Irrespective of prior treatment, in the setting of distant metastatic disease, and resectable, recurrent locoregional disease, the appropriate treatment is specified by the American Society of Clinical Oncology guidelines ( 5 ).…”

Section: Treatmentmentioning

confidence: 99%

MicroRNA in adenoid cystic carcinoma (Review)

et al. 2022

Int J Oncol

View full text Add to dashboard Cite

Adenoid cystic carcinoma (ACC) usually arises in the salivary glands, and is a rare tumor, accounting for 1% of all head and neck cancer cases. According to estimates, there are 3-4.5 cases of ACC for every one million individuals. Numerous studies have reported the association between ACC and microRNAs (miRNAs/miRs). miRNAs are endogenous, non-coding small RNAs, 19-25 nt in length, that can regulate target gene expression at the post-transcriptional level. The aberrant expression of miRNAs may be associated with the prognosis and treatment of patients, as well as with tumorigenesis and tumor development. miRNAs are becoming reliable biomarkers for disease detection due to their varied characteristics, and miRNA target-based therapies are increasingly being used in clinical practice. The present review provides a brief introduction to ACC and the biogenesis of miRNAs. A summary of the miRNAs that have been validated by in vitro or in vivo studies is then presented, describing their role in ACC. Contents1. Introduction 2. Clinical features 3. Histopathology and diagnostic imaging 4. Treatment 5. Biogenesis of miRNAs 6. miRNAs in ACC 7. Conclusions and future perspectives

show abstract

Advanced adenoid cystic carcinoma of the skull base – The role of surgery

Cited by 11 publications

References 32 publications

Posterior fossa giant adenoid cystic carcinoma with skull base invasion mimicking glomus jugulare: A case report and review of literature

Posterior fossa giant adenoid cystic carcinoma with skull base invasion mimicking glomus jugulare: A case report and review of literature

Adenoid cystic carcinoma of jugular foramen

MicroRNA in adenoid cystic carcinoma (Review)

Contact Info

Product

Resources

About