Adults' views and experiences of vaccines developed in response to the COVID-19 pandemic: a qualitative evidence synthesis

Abstract

Adults' views and experiences of vaccines developed in response to the COVID-19 pandemic: a qualitative evidence synthesis (Protocol).

Towards a More Critical Public Health Understanding of Vaccine Hesitancy: Key Insights from a Decade of Research

“…Distrust has become a pervasive concept in the literature for understanding vaccine hesitancy and what drives it [ 37 , 42 ]. Like others, we have found that a major driver of vaccine hesitancy is people’s distrust in the experts, institutions, or systems implicated with vaccination, including for example scientists, the government, the state-run healthcare system, and the pharmaceutical industry [ 20 , 21 , 22 , 28 ]. This distrust emerged in our research as a significant determinant of vaccine hesitancy for various vaccines, amongst numerous populations and within many settings.…”

“…For example, in our global and regional systematic reviews, we found that hesitancy towards HPV vaccination was uniquely connected to sociocultural norms surrounding adolescence, sexuality, and gender, and the values people attach to different sexual practices and sexualities [ 21 , 24 ]. Relatedly, it emerged from our research globally [ 22 ] and in South Africa [ 28 ] that COVID-19 vaccine hesitancy was often driven by concerns about the novelty of the vaccine and speed at which it was developed, which are concerns that did not emerge in the case of more routine vaccines that have been around for many years. Similarly, in our global systematic review, we found that the drivers of hesitancy towards routine childhood vaccines were potentially different for parents from higher and lower resource settings [ 20 ].…”

“…Our research has, however, revealed that the so-called ‘supply/access-related’ and ‘demand-related’ dimensions of vaccination are deeply intertwined and often interact in complex ways [ 20 , 21 , 22 , 28 ]. For example, across all our studies, we have found that socioeconomic challenges in accessing vaccination services, such as practical questions of geography and transport, competing priorities, and family economics and household work pressures, often contribute to vaccine hesitancy due to the time, effort, and opportunity costs that accessing vaccination involves.…”

“…Against this backdrop, over the last decade, we have conducted several qualitative social science studies with the broadly shared aim of understanding vaccine hesitancy better, including what it is, what drives it, and how it might be addressed. Specifically, we have conducted various Cochrane systematic reviews of qualitative research on the nature and drivers of vaccine hesitancy globally for routine childhood vaccines [ 20 ] human papillomavirus (HPV) vaccination for adolescents [ 21 ], and COVID-19 [ 22 ]. We have also conducted two systematic reviews of qualitative research in Africa, with one focusing on vaccine hesitancy for routine childhood vaccines [ 23 ] and the other on HPV vaccination for adolescents [ 24 ].…”

Perceptions and Intentions around Uptake of the COVID-19 Vaccination among Older People: A Mixed-Methods Study in Phuket Province, Thailand

“…From early on in the COVID-19 pandemic, vaccines, along with the wearing of face masks, social distancing, and advice around hand washing, were central public health interventions to control the spread of infection and contribute to achieving herd immunity and reducing the risk of severe illness [1]. During the pandemic, as new vaccines emerged, the WHO authorized a number of vaccines for emergency use globally, including Oxford-AstraZeneca, Johnson & Johnson, Pfizer-BioNTech, Moderna, Sputnik V, and Sinovac.…”