Adult vertebrate behavioural aquatic toxicology: Reliability and validity

Parker, Matthew O.

doi:10.1016/j.aquatox.2015.09.001

Cited by 31 publications

(29 citation statements)

References 67 publications

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“…Cameras to track organisms’ positions in 3 dimensions ( x , y , and z coordinates) and to analyze swimming behavior (Kang et al ), as well as online monitoring systems that include metabolism and behavior (Qi et al ), have also been developed and applied as tools to help in assessing the toxicity potential of contaminants. Reviews by Melvin and Wilson () and Parker () discuss the use of behavior in ecotoxicology in detail. Behavioral responses have also been used to predict other biological interactions.…”

Section: Spatial Avoidance and Habitat Preference Versus Behavioral Ementioning

confidence: 99%

Spatial avoidance as a response to contamination by aquatic organisms in nonforced, multicompartmented exposure systems: A complementary approach to the behavioral response

Araújo¹,

Blasco²

2018

Enviro Toxic and Chemistry

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The idea that the hazard of contaminants is exclusively related to their toxic effects does not consider the fact that some organisms can avoid contamination, preventing toxicity. Although inferences about avoidance are made in most behavioral ecotoxicology studies, assessment of the real spatial displacement (organisms moving toward another habitat to escape contamination) is difficult due to the type of exposure (confined and mandatory) used in the bioassays: a forced exposure approach. A complementary approach using nonforced exposure systems to assess how contaminants affect the spatial distribution of organisms in a bicompartmented (toxic or nontoxic) environment has long been described. Recently, this nonforced approach has been developed to include a multi compartmented system in which different samples can be simultaneously tested. The aim of the present review was to describe the importance of the nonforced, multicompartmented exposure approach to simulate a gradient or patches of contamination, to describe the 2 main exposure systems, and to highlight the ecological relevance of including spatial avoidance and habitat preference in ecotoxicological studies. The multicompartmentalization of the system makes it possible to simulate more complex scenarios and therefore include new ecological concepts in bioassays. We also contrasted spatial avoidance in the nonforced exposure systems with the behavioral endpoints measured under other exposure systems. Finally, we showed that the nonforced, multicompartmented exposure approach makes it possible 1) to improve environmental risk assessments by adding the dispersion pattern of organisms in a multihabitat scenario, and 2) to integrate ecological concepts such as recolonization of recovering habitats, loss of habitat connectivity, habitat fragmentation, and contamination-driven metapopulation, which have received limited attention in ecotoxicological studies. Environ Toxicol Chem 2019;38:312-320. C 2018 SETAC

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Section: Spatial Avoidance and Habitat Preference Versus Behavioral Ementioning

confidence: 99%

Spatial avoidance as a response to contamination by aquatic organisms in nonforced, multicompartmented exposure systems: A complementary approach to the behavioral response

Araújo¹,

Blasco²

2018

Enviro Toxic and Chemistry

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“…The available tools for N. furzeri , such as a whole‐brain atlas (D'Angelo ), age‐related histopathological analyses, an annotated genome and transcriptome (Di Cicco et al ; Reichwald et al ; Valenzano et al ), and the generation of transgenic lines have added to the value of N. furzeri as a model species in ecotoxicology. Furthermore, as the need to unravel the underlying physiological and biochemical mechanisms of behavioral expression is increasingly emphasized (Sloman and McNeil ; Parker , Thoré et al ), these tools could aid in the further advancement of behavioral ecotoxicology. The overall aim of the present study was to investigate the potential of N. furzeri as a model in behavioral ecotoxicology.…”

Section: Introductionmentioning

confidence: 99%

Improving the reliability and ecological validity of pharmaceutical risk assessment: Turquoise killifish (Nothobranchius furzeri) as a model in behavioral ecotoxicology

Thoré

Steenaerts

Philippe

et al. 2018

Enviro Toxic and Chemistry

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Pharmaceuticals are essential for human well‐being, but their increasing and continuous use pollutes the environment. Although behavioral ecotoxicology is increasingly advocated to assess the effects of pharmaceutical pollution on wildlife and ecosystems, a consensus on the actual environmental risks is lacking for most compounds. The main limitation is the lack of standardized reproducible tests that are based on sensitive behavioral endpoints and that accommodate a high ecological relevance. In the present study, we assessed the impact of a 3‐wk exposure to the antidepressant fluoxetine on multiple behavioral traits in the promising new model organism Nothobranchius furzeri (turquoise killifish). Overall, our study shows that fluoxetine can impact feeding behavior, habitat choice in a novel environment, and antipredator response of N. furzeri individuals; effects on spontaneous activity and exploration tendency were less pronounced. However, effects became only apparent when individuals were exposed to fluoxetine concentrations that were 10 times higher than typical concentrations in natural aquatic environments. Ecotoxicologists are challenged to maximize both the reliability and ecological validity of risk assessments of pollutants. Our study contributes to the development of a time‐ and cost‐efficient, standardized ecotoxicological test based on sensitive, ecologically relevant behavioral endpoints in N. furzeri. Environ Toxicol Chem 2019;38:262–270. © 2018 SETAC

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“…However, despite its growing recognition, the use of behavioural endpoints is currently limited by our understanding of the baseline unconditioned behaviours of many organisms, and the relevance of these behaviours to higher level effects (Melvin and Wilson, 2013). In recent years, advancements in computational equipment have provided the means for more sensitive analysis of a wider variety of complex behavioural end points, as well as improving the repeatability of bioassays (Parker, 2016;Pyle and Ford, 2017). Alongside advancements in behavioural automaton has been a rise in calls for the development and optimisation of techniques for behaviour analysis in ecotoxicology, to improve the reliability of assays, and allow for integration of complex behaviours into high-throughput assays.…”

Section: Introductionmentioning

confidence: 99%

Species-specific behaviours in amphipods highlight the need for understanding baseline behaviours in ecotoxicology

Kohler

Parker²,

Ford

2018

Aquatic Toxicology

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Adult vertebrate behavioural aquatic toxicology: Reliability and validity

Cited by 31 publications

References 67 publications

Spatial avoidance as a response to contamination by aquatic organisms in nonforced, multicompartmented exposure systems: A complementary approach to the behavioral response

Spatial avoidance as a response to contamination by aquatic organisms in nonforced, multicompartmented exposure systems: A complementary approach to the behavioral response

Improving the reliability and ecological validity of pharmaceutical risk assessment: Turquoise killifish (Nothobranchius furzeri) as a model in behavioral ecotoxicology

Species-specific behaviours in amphipods highlight the need for understanding baseline behaviours in ecotoxicology

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