Adult Utilization of Psychiatric Drugs and Differences by Sex, Age, and Race

Moore, Thomas J.; Mattison, Donald R.

doi:10.1001/jamainternmed.2016.7507

Cited by 185 publications

(154 citation statements)

References 1 publication

Supporting

Mentioning

140

Contrasting

Unclassified

Order By: Relevance

“…Female survivors were more often prescribed anxiolytics and hypnotics than male survivors. This also applied to the controls and is compatible with what is seen in the general population . Still, with higher HR, the risk of prescription seems to be higher for men.…”

Section: Discussionsupporting

confidence: 83%

Increased prescription rates of anxiolytics and hypnotics to survivors of cancer in childhood, adolescence, and young adulthood—A population‐based study

Johannsdottir

Loge

Kiserud

et al. 2017

Pediatric Blood & Cancer

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 83%

Increased prescription rates of anxiolytics and hypnotics to survivors of cancer in childhood, adolescence, and young adulthood—A population‐based study

Johannsdottir

Loge

Kiserud

et al. 2017

Pediatric Blood & Cancer

View full text Add to dashboard Cite

show abstract

“…In the past 2 decades, the use of psychotropic medications has dramatically increased: 1 out of 6 US adults is reported to take psychiatric drugs at least once during a year and in 8 out of 10 cases it is for long-term use [63]. Antidepressant drugs lead the ranking of medications [63].…”

Section: Assessing Iatrogenic Psychopathologymentioning

confidence: 99%

“…Antidepressant drugs lead the ranking of medications [63]. A further issue has to do with the frequent practice of polypharmacy in medicine [64] and psychiatry [65].…”

Section: Assessing Iatrogenic Psychopathologymentioning

confidence: 99%

Iatrogenic Factors in Psychopathology

Fava

Rafanelli

2019

Psychother Psychosom

View full text Add to dashboard Cite

“…Yet, it is astonishing how similar problems are ignored in psychotropic drug trials. Currently, 1 out of 6 adults in the USA is taking psychotropic drugs, in the majority of cases for long-term use [23]. Various forms of tolerance (e.g., resistance upon rechallenge, loss of clinical effect) and dependence may occur with the drugs and are likely to affect treatment response [24,25,26,27,28].…”

Section: Treatment Outcome As a Multifactorial Productmentioning

confidence: 99%

The Clinical Inadequacy of the Placebo Model and the Development of an Alternative Conceptual Framework

Fava

Guidi

Rafanelli

et al. 2017

Psychother Psychosom

View full text Add to dashboard Cite

Placebo effects are often attributed to clinical interactions and contextual factors that affect expectations of the patient about the treatment and result in symptom changes. The prevailing conceptualization consists of an undifferentiated placebo response that needs to be minimized in controlled investigations and maximized in clinical practice. However, treatment outcome is the cumulative result of the interaction of several classes of variables with a selected treatment: living conditions (housing, nutrition, work environment, social support), patient characteristics (age, sex, genetics, general health conditions, personality, well-being), illness features and previous therapeutic experience, self-management, and treatment setting (physician's attitude and attention, illness behavior). Such variables may be therapeutic or countertherapeutic, and are unlikely to be simply additive. In certain patients their interactive combination may lead to clinical improvement, whereas in other cases it may produce no effect, and, in a third group, it may lead to worsening of the condition. Maximizing patients' expectations does not necessarily result in sustained effects and, in due course, may actually lead to worsening of the condition (violation of expectations). In this paper, we outline a multifactorial conceptual model that may have implications for the design of clinical trials as well as for clinical practice, with special reference to psychopharmacology and psychotherapy. The effects of drug treatment may be potentiated by specific nonpharmacological treatment strategies, and this synergism may disclose significant differences against placebo. Medical outcomes may be unsatisfactory not because technical interventions are missing, but because our conceptual models and thinking are inadequate.

show abstract

Adult Utilization of Psychiatric Drugs and Differences by Sex, Age, and Race

Abstract: findings should be confirmed by future studies involving diverse groups of older adults.

Cited by 185 publications

References 1 publication

Increased prescription rates of anxiolytics and hypnotics to survivors of cancer in childhood, adolescence, and young adulthood—A population‐based study

Increased prescription rates of anxiolytics and hypnotics to survivors of cancer in childhood, adolescence, and young adulthood—A population‐based study

Iatrogenic Factors in Psychopathology

The Clinical Inadequacy of the Placebo Model and the Development of an Alternative Conceptual Framework

Contact Info

Product

Resources

About