Adult renal myoepithelial hamartoma

Fischer, C. Peter; Herwig, Karl R.; Gikas, Paul W.

doi:10.1016/0090-4295(78)90483-1

Cited by 8 publications

(4 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An adult renal myoepithelial hamartoma was easily excluded on morphologic basis. 8 As a more consistent alternative, metanephric adenoma is also composed by low cuboidal shape of the tumor cells, minimal cytoplasm and interanastomoting tubular pattern, but typically lacks a myxoid stroma and the epithelial cells show a basophilic cytoplasm. Additionally, metanephric adenomas differ from the present lesion in that they are never diffusely reactive for cytokeratin 7 and are completely nonreactive for epithelial membrane antigen.…”

Section: Discussionmentioning

confidence: 99%

Myxoid Renal Tumor With Myoepithelial Differentiation Mimicking a Salivary Gland Pleomorphic Adenoma: Description of a Case

Pacchioni¹,

Volante²,

Casetta

et al. 2007

American Journal of Surgical Pathology

View full text Add to dashboard Cite

We herein report an unusual case of a low-grade myxoid renal epithelial neoplasm, with peculiar and previously unreported morphologic and immunohistochemical features. The lesion was characterized by noninfiltrative borders, myxoid stroma and elongated tubular and cordlike epithelial structures. These were lined by 2 different epithelial cell types, flat and elongated basal cells and cuboidal to spindle shaped eosinophilic luminal cells, with low-grade nuclear features and a few small nucleoli. The lesion morphologically resembled a pleomorphic adenoma of the salivary gland. The immunohistochemical profile interestingly confirmed the myoepithelial differentiation of the basal epithelial layer, as demonstrated by the coexpression of several myoepithelial markers such as p63, caldesmon, calponin, smooth muscle actin, and S-100, together with epithelial markers such as low and high-molecular weight cytokeratins. The tumor proved benign at follow-up. A definitive classification and histogenetic interpretation of this previously unreported tumor type awaits description of further cases showing similar features which, perhaps, as it may happen, went so far unnoticed.

show abstract

Section: Discussionmentioning

confidence: 99%

Myxoid Renal Tumor With Myoepithelial Differentiation Mimicking a Salivary Gland Pleomorphic Adenoma: Description of a Case

Pacchioni¹,

Volante²,

Casetta

et al. 2007

American Journal of Surgical Pathology

View full text Add to dashboard Cite

show abstract

“…Mesoblastic nephroma was first described by Bolande 20 in 1973 as a benign renal tumor in childhood and the mean age at diagnosis for congenital mesoblastic nephroma is 3.5 months. 21 In the literature we found only 22 cases of mesoblastic nephroma of adults in the kidney including our case [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] (Table 1).…”

Section: Discussionmentioning

confidence: 99%

“…8,12 Macroscopically, cystic lesions were seen in seven cases (31.8%). 2,3,5,6,11,12,14 Twenty-two percent of renal cell carcinomas were reported to show hypovascular lesions on arteriography. 23 Therefore, we could not deny the malignant disease, such as renal cell carcinoma, with any diagnostic modalities.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Mesoblastic nephroma in adulthood: A case report

Shiraishi

Yamamoto²,

Gondo

et al. 1999

Int J of Urology

View full text Add to dashboard Cite

Background: Mesoblastic nephroma is an uncommon renal tumor of infancy and rarely occurs in adults. We report an adult case of mesoblastic nephroma. Methods: A 50-year-old woman was found incidentally to have a right renal mass by abdominal ultrasonography. Computed tomography and magnetic resonance imaging revealed a heterogeneous tumor and angiography showed a mixture of hypervascularity and hypovascularity. Right radical nephrectomy was performed. Results:The tumor was an encapsulated yellowish solid mass. Microscopically, the tumor was composed of spindle cell proliferation. Atypia and mitoses were not identified. Among the tumor cells, there were tubular arranged epithelial elements. Conclusion:The patient was free of recurrence 14 months postoperatively. Mesoblastic nephroma is classified as a benign tumor but recurrence and malignant formation of this tumor have been reported so regular postoperative follow up is required.

show abstract