Adult-onset Still’s disease as a cutaneous marker of systemic disease

Damevska, Katerina; França, Katlein; Nikolovska, Suzana; Gucev, Filip

doi:10.1016/j.clindermatol.2019.07.034

Cited by 6 publications

(2 citation statements)

References 71 publications

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“…Rarely, AOSD can involve internal organs, such as the liver, and even less commonly, the lungs. There can be associated underlying malignancies including lymphomas, solid tumors, and hematopoietic cancers [1][2][3][4][5]. Dermatologically, patients with classic AOSD present with an asymptomatic, salmon-pink to erythematous eruption comprised of evanescent macules, patches, and papules.…”

Section: Discussionmentioning

confidence: 99%

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Persistent, Pruritic, Reddish-Brown Papules and Plaques: An Atypical Presentation of Adult-Onset Still’s Disease

Whittington¹,

Lapides²,

Morley³

et al. 2023

Cureus

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Adult-onset Still's disease (AOSD) is a systemic inflammatory condition characterized by recurrent fevers and a dermatologic eruption. The eruption is classically described as migratory and evanescent, composed of salmon-pink to erythematous macules, patches, and papules. However, a much rarer skin rash can also be seen in the setting of AOSD. This eruption has a different morphology, appearing as fixed, extremely pruritic papules and plaques. The histology of this atypical form of AOSD is distinct from that of the more common evanescent eruption. Management of AOSD is multi-faceted, aimed at controlling both the acute and chronic phases. Increased awareness of this more uncommon cutaneous presentation of AOSD is vital so that the appropriate diagnosis can be rendered. Herein, the authors describe an atypical presentation of AOSD in a 44-year-old male patient who presented with persistent, pruritic, brownish papules and plaques on the trunk and extremities.

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Section: Discussionmentioning

confidence: 99%

“…This eruption tends to appear during fever spikes, but then disappears once the fevers resolve. Most commonly, the rash involves the trunk, but can spread to the upper and lower extremities [ 2 ].…”

Section: Discussionmentioning

confidence: 99%